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| **<font inherit/inherit;;#c0392b;;inherit>Scientific Webinar Calendar:</font> ** [[https://4dnucleome-org.zoom.us/meeting/tJEsc-ytrDksEtWNHy00h-5RmkNx7equ3Nca/ics?icsToken=98tyKuCtrz8vH9aXthGGRowMBY-gZ-_zpnpdj7dqsjf8U3BbL1bEO-lsKuV6Ac2D|click here]] to add all the Scientific Webinar events to your personal calendar | **<font inherit/inherit;;#c0392b;;inherit>Scientific Webinar Calendar:</font> ** [[https://4dnucleome-org.zoom.us/meeting/tJEsc-ytrDksEtWNHy00h-5RmkNx7equ3Nca/ics?icsToken=98tyKuCtrz8vH9aXthGGRowMBY-gZ-_zpnpdj7dqsjf8U3BbL1bEO-lsKuV6Ac2D|click here]] to add all the Scientific Webinar events to your personal calendar | ||
| - | <font inherit/inherit;;#c0392b;;inherit>**Scientific Webinar Assignments (2021-2024):**</font> [[http://docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing|docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing]] | + | <font inherit/inherit;;#c0392b;;inherit>**Scientific Webinar Assignments (2021-2025):**</font> [[http://docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing|docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing]] |
| ===== Mission ===== | ===== Mission ===== | ||
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| ===== Scientific Webinar Series slides presentations ===== | ===== Scientific Webinar Series slides presentations ===== | ||
| - | **October 27, 2023** | + | **August 22, 2025** |
| - | **Moderator: Yin Shen** | + | **Zoom recording link** |
| - | **Presenter: ****Ariel Pourmorady **//(Columbia University////)// - //**“A symmetry breaking process proposes noncoding functions for olfactory receptor RNAs” **// ([[https://docs.google.com/presentation/d/1OUDaikuuJ57YneQHFei5hOaPDWOzqA10/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]]) | + | **Moderator: Yuan Liu** |
| - | **Presenter: Bence Daniel **//(Stanford University)//** - **//**“****Macrophage plasticity in the 3-dimensional genome****”** // ([[https://docs.google.com/presentation/d/1VlMyi6t3dql0p3wkxA9JuW0-iI4KK2yR/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]]) | + | |
| - | * Scientific Webinar presentations (Phase 1) can be found [[https://wiki.4dnucleome.org/4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|here]]. | + | **Presenter: Jodi Lee **//(University of California, San Francisco) //**-** //**"Predictive modeling to assess the role of 3D genome folding in human congenital heart disease"**// ([[https://drive.google.com/file/d/11mB2tB0l9egVjxAfJckfR3CKb3hy0qxe/view?usp=sharing|Link to presenter slides]]) |
| + | **Presenter: Yanyu Zhu** //(Stanford University) //- **//“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”//** ([[https://docs.google.com/presentation/d/1o9bXE1ZnWB0bxaXBYzDf1GE14dgzolUx/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]]) | ||
| + | |||
| + | * Scientific Webinar presentations (Phase 1) can be found [[https://wiki.4dnucleome.org/4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|here]]. | ||
| * Scientific Webinar presentations (Phase 2) can be found [[https://wiki.4dnucleome.org/4dn:phase2:scientific_webinar_archive|here]]. | * Scientific Webinar presentations (Phase 2) can be found [[https://wiki.4dnucleome.org/4dn:phase2:scientific_webinar_archive|here]]. | ||
| ===== 4DN Scientific Webinar Series ===== | ===== 4DN Scientific Webinar Series ===== | ||
| - | <font 16px/inherit;;inherit;;inherit>**October 27, 2023**</font> | + | <font 16px/inherit;;inherit;;inherit>**August 22, 2025**</font> |
| <font 14px/inherit;;inherit;;inherit>**8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)**</font> | <font 14px/inherit;;inherit;;inherit>**8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)**</font> | ||
| - | {{:4dn:phase2:pourmorady_ariel_480.png?direct&200}} | + | **Jodi Lee** |
| - | **Ariel Pourmorady** | + | **Grad Student** |
| - | **MD-PhD Student** | + | [[jodi.lee@gladstone.ucsf.edu|]] |
| - | [[adp2164@cumc.columbia.edu|]] | + | **Title: //“Predictive modeling to assess the role of 3D genome folding in human congenital heart disease”// ** |
| - | **Title: **//**"A symmetry breaking process proposes noncoding functions for olfactory receptor RNAs"** // | + | Jodi is a 4th year graduate student studying genetics in Dr. Katherine Pollard’s Lab at the University of California, San Francisco. Jodi’s research focuses on creating and working with deep learning models to study the complex DNA sequence grammar regulating the genome. Currently, she is leveraging Cardiac-Akita, a DNA sequence to 3D genome folding deep learning model, to predict how genetic variants associated with congenital heart defects disrupt 3D genome contacts. |
| - | + | ||
| - | I am currently a 6th year MD-PhD student at Columbia University in the lab of Dr. Stavros Lomvardas. As a graduate student my research has been primarily focused on clarifying the genomic transformations that take place to facilitate olfactory receptor choice in the mouse main olfactory epithelium. I have used a variety of single-cell genomics technologies as well as mouse genetics to uncover a differentiation-dependent process whereby olfactory receptor genes compete for transcriptional selection. Broadly, I am interested in understanding how neurons employ gene regulatory programs—modifying chromatin state, nuclear architecture, and more—to support normal cell development and function. | + | |
| <font 14px/inherit;;inherit;;inherit>**8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)**</font> | <font 14px/inherit;;inherit;;inherit>**8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)**</font> | ||
| - | {{:4dn:phase2:daniel_bence_720.jpg?direct&200|daniel_bence_720.jpg}} | + | **Yanyu Zhu** |
| - | **Bence Daniel** | + | **Postdoctoral Researcher** |
| - | **Principal Scientist** | + | [[yanyuzhu@stanford.edu|]] |
| - | //[[bdaniel8@stanford.edu|]]// | + | **Title: //“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”// ** |
| - | **Title:// “// **//**Macrophage plasticity in the 3-dimensional genome** //**//”//** Bence Daniel is a Principal Scientist at Genentech where he is leading the Epigenetics and Chromatin Biology Research Program in the MPL-NGS Department. Bence was a postdoctoral fellow in the Satpathy lab at Stanford University where he studied the epigenetic regulation of T cell exhaustion in viral infection and cancer, and macrophage responses to inflammatory signals as part of the 4D Nucleome program. More specifically, he investigated how epigenetic programs and genome conformation affect macrophage plasticity, memory formation, and inflammatory signal integration. | + | Yanyu Zhu is a postdoctoral researcher in Prof. Stanley Qi’s Lab in the Department of Bioengineering at Stanford University. He obtained his B.S. in Chemistry from Peking University and his Ph.D. in Chemistry from the University of Wisconsin–Madison. In collaboration with Prof. W. E. Moerner’s lab, he developed and applied a high-resolution, reagent-based DNA imaging platform, Oligo-LiveFISH, to investigate 3D chromatin dynamics in live cells. His current research focuses on applying Oligo-LiveFISH to study various biological questions such as the relationship between the 3D genome and gene regulation in real time, as well as investigating the dynamic process of DNA repair. |
| - | ===== HOW TO Join the Webinar ===== | + | |
| The Webinar Series will be on the **4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.** | The Webinar Series will be on the **4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.** | ||
| - | 4DN OH is inviting you to a scheduled Zoom meeting. | + | **4DN OH is inviting you to a scheduled Zoom meeting.** |
| Topic: 4DN Scientific Webinar\\ Please download and import the following iCalendar (.ics) files to your calendar system.\\ Monthly: [[https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f|https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f]] | Topic: 4DN Scientific Webinar\\ Please download and import the following iCalendar (.ics) files to your calendar system.\\ Monthly: [[https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f|https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f]] | ||
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| <font 16px/inherit;;inherit;;inherit>**Next Scientific Webinar Presentation**</font> | <font 16px/inherit;;inherit;;inherit>**Next Scientific Webinar Presentation**</font> | ||
| - | |||
| - | **When: January 26, 2024** | ||
| - | |||
| - | **Moderator: Sui Huang** | ||
| - | |||
| - | * Presenter from **Tomoko Yamada**'**s team ** | ||
| - | * Presenter from **Thomas Gregor (contact), Michael Levine, Jared Toettcher****'s** team | ||