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**<font inherit/inherit;;#c0392b;;inherit>Scientific Webinar Calendar:</font> ** [[https://4dnucleome-org.zoom.us/meeting/tJEsc-ytrDksEtWNHy00h-5RmkNx7equ3Nca/ics?icsToken=98tyKuCtrz8vH9aXthGGRowMBY-gZ-_zpnpdj7dqsjf8U3BbL1bEO-lsKuV6Ac2D|click here]] to add all the Scientific Webinar events to your personal calendar | **<font inherit/inherit;;#c0392b;;inherit>Scientific Webinar Calendar:</font> ** [[https://4dnucleome-org.zoom.us/meeting/tJEsc-ytrDksEtWNHy00h-5RmkNx7equ3Nca/ics?icsToken=98tyKuCtrz8vH9aXthGGRowMBY-gZ-_zpnpdj7dqsjf8U3BbL1bEO-lsKuV6Ac2D|click here]] to add all the Scientific Webinar events to your personal calendar | ||
- | <font inherit/inherit;;#c0392b;;inherit>**Scientific Webinar Assignments (2021-2024):**</font> [[http://docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing|docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing]] | + | <font inherit/inherit;;#c0392b;;inherit>**Scientific Webinar Assignments (2021-2025):**</font> [[http://docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing|docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing]] |
===== Mission ===== | ===== Mission ===== | ||
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===== Scientific Webinar Series slides presentations ===== | ===== Scientific Webinar Series slides presentations ===== | ||
- | **February 23, 2024** | + | **August 22, 2025** |
- | **Moderator: Ting Wang** | + | **Zoom recording link** |
- | **Presenter: Benxia Hu**//(University of Texas Health Science Center Houston////)// - **//“// **//**m6A-MAPT-uaRNA regulates gene expression in Alzheimer’s disease****"**// (Link to presenter slides) | + | **Moderator: Yuan Liu** |
- | **Presenter: Alex Polyzos **//(////Weill Cornell Medicine)//** - //“// **//**Mapping of 3D enhancer-promoter networks in early embryonic lineages and predictions of regulatory relationships****”** // ([[https://docs.google.com/presentation/d/10BCZlphzT-05uA7qgrer2vnz1AV-2X8Z/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]]) | + | **Presenter: Jodi Lee **//(University of California, San Francisco) //**-** //**"Predictive modeling to assess the role of 3D genome folding in human congenital heart disease"**// ([[https://drive.google.com/file/d/11mB2tB0l9egVjxAfJckfR3CKb3hy0qxe/view?usp=sharing|Link to presenter slides]]) |
- | * Scientific Webinar presentations (Phase 1) can be found [[https://wiki.4dnucleome.org/4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|here]]. | + | **Presenter: Yanyu Zhu** //(Stanford University) //- **//“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”//** ([[https://docs.google.com/presentation/d/1o9bXE1ZnWB0bxaXBYzDf1GE14dgzolUx/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]]) |
+ | * Scientific Webinar presentations (Phase 1) can be found [[https://wiki.4dnucleome.org/4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|here]]. | ||
* Scientific Webinar presentations (Phase 2) can be found [[https://wiki.4dnucleome.org/4dn:phase2:scientific_webinar_archive|here]]. | * Scientific Webinar presentations (Phase 2) can be found [[https://wiki.4dnucleome.org/4dn:phase2:scientific_webinar_archive|here]]. | ||
===== 4DN Scientific Webinar Series ===== | ===== 4DN Scientific Webinar Series ===== | ||
- | <font 16px/inherit;;inherit;;inherit>**February 23, 2024**</font> | + | <font 16px/inherit;;inherit;;inherit>**August 22, 2025**</font> |
<font 14px/inherit;;inherit;;inherit>**8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)**</font> | <font 14px/inherit;;inherit;;inherit>**8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)**</font> | ||
- | {{:4dn:phase2:benxiahu_480.jpg?direct&200|benxiahu_480.jpg}} | + | **Jodi Lee** |
- | **Benxia Hu** | + | **Grad Student** |
- | **Postdoc** | + | [[jodi.lee@gladstone.ucsf.edu|]] |
- | [[Benxia.Hu@uth.tmc.edu|]] | + | **Title: //“Predictive modeling to assess the role of 3D genome folding in human congenital heart disease”// ** |
- | **Title: **//**"** ////**m6A-MAPT-uaRNA regulates gene expression in Alzheimer’s disease****"** // | + | Jodi is a 4th year graduate student studying genetics in Dr. Katherine Pollard’s Lab at the University of California, San Francisco. Jodi’s research focuses on creating and working with deep learning models to study the complex DNA sequence grammar regulating the genome. Currently, she is leveraging Cardiac-Akita, a DNA sequence to 3D genome folding deep learning model, to predict how genetic variants associated with congenital heart defects disrupt 3D genome contacts. |
- | Dr. Benxia Hu is a postdoctoral researcher in Dr. Wenbo Li’s lab at University of Texas Health Science Center Houston. He earned his Ph.D. from the Kunming Institute of Zoology, Chinese Academy of Sciences. Benxia's interest is on unraveling roles of 3D genome architectures in the human brains. Currently, his interest is to decipher the role of MAPT-uaRNA in the Alzheimer’s disease. | + | <font 14px/inherit;;inherit;;inherit>**8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)**</font> |
- | <font 14px/inherit;;inherit;;inherit>**8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)**</font>**TBD** | + | **Yanyu Zhu** |
- | {{:4dn:phase2:img_6496_720.jpg?direct&200|img_6496_720.jpg}} | + | **Postdoctoral Researcher** |
- | **Alex Polyzos** | + | [[yanyuzhu@stanford.edu|]] |
- | **Assistant Professor** | + | **Title: //“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”// ** |
- | [[app2006@med.cornell.edu|]] | + | Yanyu Zhu is a postdoctoral researcher in Prof. Stanley Qi’s Lab in the Department of Bioengineering at Stanford University. He obtained his B.S. in Chemistry from Peking University and his Ph.D. in Chemistry from the University of Wisconsin–Madison. In collaboration with Prof. W. E. Moerner’s lab, he developed and applied a high-resolution, reagent-based DNA imaging platform, Oligo-LiveFISH, to investigate 3D chromatin dynamics in live cells. His current research focuses on applying Oligo-LiveFISH to study various biological questions such as the relationship between the 3D genome and gene regulation in real time, as well as investigating the dynamic process of DNA repair. |
- | + | ||
- | **Title:// “// **//**Mapping of 3D enhancer-promoter networks in early embryonic lineages and predictions of regulatory relationships** //**//”//** Alex is an Assistant Professor of Molecular Biology, Research in Medicine in Weill Cornell Medicine. He joined Effie's Apostolou lab as a post-doc in 2017 and focused his research on investigating the organization of the 3D genome. His interest lies in characterizing the properties of 3D enhancer and promoter networks (referred to as HUB) and exploring how the rewiring of HUBs influences gene expression during somatic cell reprogramming, development and tumorigenesis. | + | |
- | ===== HOW TO Join the Webinar ===== | + | |
The Webinar Series will be on the **4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.** | The Webinar Series will be on the **4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.** | ||
- | 4DN OH is inviting you to a scheduled Zoom meeting. | + | **4DN OH is inviting you to a scheduled Zoom meeting.** |
Topic: 4DN Scientific Webinar\\ Please download and import the following iCalendar (.ics) files to your calendar system.\\ Monthly: [[https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f|https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f]] | Topic: 4DN Scientific Webinar\\ Please download and import the following iCalendar (.ics) files to your calendar system.\\ Monthly: [[https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f|https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f]] | ||
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<font 16px/inherit;;inherit;;inherit>**Next Scientific Webinar Presentation**</font> | <font 16px/inherit;;inherit;;inherit>**Next Scientific Webinar Presentation**</font> | ||
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- | **When: March 22, 2024** | ||
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- | **Moderator: Taekjip Ha** | ||
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- | * Presenter from **David Schatz (contact), Siyuan Wang**'**s team ** | ||
- | * Presenter from **Yin Shen (contact), Arnold Kriegstein****'s** team | ||