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--- 4dn:phase2:scientific_webinar [2025/06/16 13:44]
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+++ 4dn:phase2:scientific_webinar [2025/08/22 08:04] (current)
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@@ Line 25: / Line 25: @@
 ===== Scientific Webinar Series slides presentations =====
-**June 27, 2025**
+**August 22, 2025**
 **Zoom recording link**
-**Moderator: Yin Shen**
+**Moderator: Yuan Liu**
-**Presenter: Siyuan Wang**// (Yale School of Medicine)//** - //“Sequencing-free whole genome spatial transcriptomics at molecular resolution in intact tissue” //** (Link to presenter slides)
+**Presenter: Jodi Lee **//(University of California, San Francisco) //**-** //**"Predictive modeling to assess the role of 3D genome folding in human congenital heart disease"**//  ([[https://drive.google.com/file/d/11mB2tB0l9egVjxAfJckfR3CKb3hy0qxe/view?usp=sharing|Link to presenter slides]])
-**Presenter: Julian Pulecio Rojas**// (Memorial Sloan Kettering)//** - //“Functional chromatin signatures preestablish future lineage-specific enhancers in embryonic stem cells”// ** (Link to presenter slides)
+**Presenter: Yanyu Zhu** //(Stanford University) //- **//“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”//**  ([[https://docs.google.com/presentation/d/1o9bXE1ZnWB0bxaXBYzDf1GE14dgzolUx/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]])
   * Scientific Webinar presentations (Phase 1) can be found [[https://wiki.4dnucleome.org/4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|here]].
@@ Line 40: / Line 40: @@
 ===== 4DN Scientific Webinar Series =====
-<font 16px/inherit;;inherit;;inherit>**June 27, 2025**</font>
+<font 16px/inherit;;inherit;;inherit>**August 22, 2025**</font>
 <font 14px/inherit;;inherit;;inherit>**8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)**</font>
-**Siyuan Wang**
+**Jodi Lee**
-**Associate Professor**
+**Grad Student**
-**[[siyuan.wang@yale.edu|]]**
+[[jodi.lee@gladstone.ucsf.edu|]]
-**Title: //“Sequencing-free whole genome spatial transcriptomics at molecular resolution in intact tissue”// **
+**Title: //“Predictive modeling to assess the role of 3D genome folding in human congenital heart disease”// **
-Siyuan (Steven) Wang, Ph. D., is an Associate Professor of Genetics and Cell Biology at Yale School of Medicine. Research in his lab focuses on the development and application of state-of-the-art image-based omics approaches to understand the spatial organization of mammalian genome and transcriptome, and how they impact cellular states. Originally from China, Dr. Wang received a Bachelor of Science degree in Physics from Peking University in 2007. He then moved to the US and received a Ph. D. in Molecular Biology from Princeton in 2011 and later his postdoctoral training at Harvard. In 2017 he was appointed Assistant Professor by Yale University, and was promoted to the rank of Associate Professor in 2023.
+Jodi is a 4th year graduate student studying genetics in Dr. Katherine Pollard’s Lab at the University of California, San Francisco. Jodi’s research focuses on creating and working with deep learning models to study the complex DNA sequence grammar regulating the genome. Currently, she is leveraging Cardiac-Akita, a DNA sequence to 3D genome folding deep learning model, to predict how genetic variants associated with congenital heart defects disrupt 3D genome contacts.
 <font 14px/inherit;;inherit;;inherit>**8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)**</font>
-**Julian Pulecio Rojas**
+**Yanyu Zhu**
-**Senior Scientist**
+**Postdoctoral Researcher**
-**[[pulecioj@mskcc.org|]]**
+[[yanyuzhu@stanford.edu|]]
-**Title: //“Functional chromatin signatures preestablish future lineage-specific enhancers in embryonic stem cells”// **
+**Title: //“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”// **
-Julian is a biologist oriented to study the mechanisms that regulate cell fate and to develop lineage conversion strategies to generate clinically relevant cell types in vitro. He works as a Senior Scientist in the laboratory of Danwei Huangfu at the Memorial Sloan Kettering and is currently in the job market to start his own laboratory. His current research aims to elucidate the epigenetic factors that support cellular plasticity in pluripotent stem cells.
+Yanyu Zhu is a postdoctoral researcher in Prof. Stanley Qi’s Lab in the Department of Bioengineering at Stanford University. He obtained his B.S. in Chemistry from Peking University and his Ph.D. in Chemistry from the University of Wisconsin–Madison. In collaboration with Prof. W. E. Moerner’s lab, he developed and applied a high-resolution, reagent-based DNA imaging platform, Oligo-LiveFISH, to investigate 3D chromatin dynamics in live cells. His current research focuses on applying Oligo-LiveFISH to study various biological questions such as the relationship between the 3D genome and gene regulation in real time, as well as investigating the dynamic process of DNA repair.
 The Webinar Series will be on the **4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.**
@@ Line 91: / Line 91: @@
 <font 16px/inherit;;inherit;;inherit>**Next Scientific Webinar Presentation**</font>
-**When: July 25, 2025**
-**Moderator: Sui Huang**
-  * Presenter from **Yin Shen (contact), Arnold Kriegstein's team**
-  * Presenter from **Xiangmin Xu (contact), Carl Cotman, Bing Ren's**  team

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