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--- 4dn:phase2:working_groups:4dnsc4all [2022/07/19 08:19]
lbintu [Overall Mission]
+++ 4dn:phase2:working_groups:4dnsc4all [2025/04/22 16:21] (current)
@@ Line 6: / Line 6: @@
 **4DN Calendar: ** [[https://wiki.4dnucleome.org/4dn:calendar_4dn|https://wiki.4dnucleome.org/4dn:calendar_4dn]] ([[https://ics.teamup.com/feed/ksrqw1wb728dtrxdvg/8852681.ics|click here]] to add this specific WG calendar to your personal calendar)
+**Previous meeting recordings: [[https://drive.google.com/drive/u/2/folders/152onkHbb_XwmR7z5d2GwiSq1I8LabaHH|https://drive.google.com/drive/u/2/folders/152onkHbb_XwmR7z5d2GwiSq1I8LabaHH]]**
 **Zoom link:** [[https://4dnucleome-org.zoom.us/j/82077914018?pwd=RUxNcWoxeG11bEJEQjRZb3IydlZFdz09|https://4dnucleome-org.zoom.us/j/82077914018?pwd=RUxNcWoxeG11bEJEQjRZb3IydlZFdz09]]
@@ Line 14: / Line 16: @@
 **Slack channel:**
 ===== Plans and Documents =====
-=====   =====
+Agenda, Minutes, and Mission:
+[[https://docs.google.com/document/d/1PuSPeug0qgnv_-DePvDLwhbaxyYvFzeqNv_eIpDp4pA/edit|https://docs.google.com/document/d/1PuSPeug0qgnv_-DePvDLwhbaxyYvFzeqNv_eIpDp4pA/edit]]
+Meetings are on Thursdays, every other week: 10:00 – 11:00am PST (in 2022: July 28, August 11, August 25, etc).
+<font inherit/inherit;;#c0392b;;inherit>**Everyone who wants to learn more or contribute ideas, data, analysis is welcome!**</font>
 ===== Overall Mission =====
@@ Line 54: / Line 64: @@
-===== Primary Experimental Technologies – Two primary single-cell technologies (imaging and omics) and their integration with existing assays (including population-based methods) to reach a more complete view of nuclear organization over time. =====
+===== Primary Experimental Technologies  =====
+Two primary single-cell technologies (imaging and omics) and their integration with existing assays (including population-based methods) to reach a more complete view of nuclear organization over time:
   * Single-cell multiomics: single nucleus methyl 3C seq (snm3C-seq) for combined DNA methylation and Hi-C in single cells, supplemented with single-cell multiomics (e.g., combined ATAC/RNA-seq).
@@ Line 63: / Line 75: @@
-===== Primary Experimental Systems – We aim to inclusively implement the primary technologies mentioned above across the following three physiologically important systems: =====
+===== Primary Experimental Systems =====
+We aim to inclusively implement the primary technologies mentioned above across the following physiologically important systems:
 **Stage 1 – Pilot Phase**
@@ Line 79: / Line 93: @@
-===== Computational Analysis and Method Development Opportunities – Computational integration, analysis, and modeling should be at the forefront along with the experimental processes. Major deliverable will include software tools, benchmark datasets and metrics, and analysis workflows to establish the “navigable maps” of nuclear architecture: =====
+===== Computational Analysis and Method Development Opportunities =====
+Computational integration, analysis, and modeling should be at the forefront along with the experimental processes. Major deliverable will include software tools, benchmark datasets and metrics, and analysis workflows to establish the “navigable maps” of nuclear architecture:
   * Algorithms for image analysis steps (fiducial localization, spot calling, segmentation, drift correction) and single-cell integrative analysis, including 3D genome feature detection (single-cell TADs/subTADs/bodies/compartments/loops)
@@ Line 90: / Line 106: @@
   * Modeling approaches to assess mechanisms of nuclear structure in space and time
-===== Plans and Documents =====

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