====== Perturbation-Differentiation ======

**Point people/organizers:** //Danwei Huangfu, Thomas Gregor, Yarui Diao, Bo Huang, Rene Maehr, Wenbo Li//

<font inherit/inherit;;#c0392b;;inherit>**4DN Google Drive folder:**</font> [[https://drive.google.com/drive/folders/1h1gU3Inwj837ZCJTyLAZ1ZUzjXOzpK9Z?usp=sharing|https://drive.google.com/drive/folders/1h1gU3Inwj837ZCJTyLAZ1ZUzjXOzpK9Z?usp=sharing]]

**<font inherit/inherit;;#c0392b;;inherit>4DN Calendar:</font> **  [[https://wiki.4dnucleome.org/4dn:calendar_4dn|https://wiki.4dnucleome.org/4dn:calendar_4dn]] ([[https://ics.teamup.com/feed/ksrqw1wb728dtrxdvg/9167298.ics|click here]] to add this specific IG calendar to your personal calendar)

**<font inherit/inherit;;#c0392b;;inherit>Agenda/Minutes:</font> **  [[https://docs.google.com/document/d/1Pbx89KsVgrfJARryD47_zfE8RZNT58ptTlOnWzYtH5o/edit?usp=sharing|https://docs.google.com/document/d/1Pbx89KsVgrfJARryD47_zfE8RZNT58ptTlOnWzYtH5o/edit?usp=sharing]]

<font inherit/inherit;;#c0392b;;inherit>**Meeting attendee spreadsheet: **</font>[[https://docs.google.com/spreadsheets/d/1P4-MTE0LDnD_J0VEZ3JtJioT5IMqELtDo23JO1XWtIw/edit?usp=sharing|https://docs.google.com/spreadsheets/d/1P4-MTE0LDnD_J0VEZ3JtJioT5IMqELtDo23JO1XWtIw/edit?usp=sharing]]

**<font inherit/inherit;;#c0392b;;inherit>Email list:</font> [[perturbation-differentiation@4dnucleome.org|]]**

**<font inherit/inherit;;#c0392b;;inherit>Slack channel:</font> **  #ig-perturbation-differentiation

===== Topic Statement =====

**The goal of the Perturbation-Differentiation IG is to facilitate communication between various 4DN labs using differentiation systems to:**

  * Coordinate efforts
  * Identify opportunities for collaboration
  * Learn from each other’s experiences and the latest exciting findings
  * Discover interesting chromatin biology during tissue differentiation and development

**and facilitate discussions and foster collaborations focused on perturbation methods including the following topics:**

  * discussion of perturbation methods across an array of genomic and cellular contexts
  * development of perturbative imaging approaches to dissect biological function
  * approaches to scale up perturbation for functional screening
  * functional screening readout with relevance to human health

//***As of April 2023, IG meetings are cancelled until further interest. //