August 23, 2019

Presenter: Andrew Stephens (Umass Amherst) - “Heterochromatin and HP1alpha provide different nuclear mechanical contributions to maintain nuclear shape and function” (Link to presenter slides)

Presenter: Yodai Takei (Caltech) - “Intron seqFISH enables spatial analysis of the nascent transcriptome in single cells” (Link to presenter slides)

Previous Scientific Webinar presentations can be downloaded from the Scientific Webinar presentation archive page linked here.

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8:00-8:20 am Pacific Time , 20 minutes talk, then 10 minutes Q&A

Andrew Stephens

Assistant Professor

andrew.stephens@northwestern.edu

Title: “Heterochromatin and HP1alpha provide different nuclear mechanical contributions to maintain nuclear shape and function”

Andrew is starting his new lab as an Assistant Professor at UMass Amherst this coming January and is currently a Postdoctoral Fellow in the Marko lab at Northwestern University. He developed a novel nucleus isolation and force measurement technique that, for the first time, was able to separate the mechanical contributions of the two main mechanical components of the cell nucleus, chromatin and lamins. His work focuses on understanding the significance of abnormal nuclear morphology which is a hallmark of human disease through understanding chromatin's role as a mechanical element of the nucleus dictating shape and function.

8:30-8:50 am Pacific Time , 20 minutes talk, then 10 minutes Q&A

Yodai Takei

Graduate student

ytakei@caltech.edu

Title: “Intron seqFISH enables spatial analysis of the nascent transcriptome in single cells”

Yodai Takei is currently a graduate student in Long Cai’s lab at Caltech, developing highly multiplexed imaging techniques for single cell genomics. Before that, he earned his undergraduate and master’s degree from the University of Tokyo.

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The 4th Friday of every month, from Friday, January 26, 2018, to no end date
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When: September 27, 2019

Moderated by: Jennifer Philips-Cremins

Member from Clifford Brangwynne's group (Presenter to be determined)

Member from Andrew Belmont's group (Jian Ma presenter)