October 27, 2017

8:00-8:20 am Pacific Time, then 10-minute discussion and Q&A

Adan Horta

MD/PhD candidate at Columbia University

horta.adan@gmail.com

Title: Interchromosomal Interactions as a Source of Neuronal Diversity

Adan Horta is 5th year MD/PhD candidate at Columbia University with interests in neuroscience, genomics, and the mechanisms underlying cellular diversity. He grew up in central Massachusetts and spent 8 years in Nashville, Tennessee for high school and college where he graduated with a double major in Neuroscience and Chemistry from Vanderbilt University in 2013.

8:30-8:50 am Pacific Time, then 10-minute discussion and Q&A

Horng Ou

Ph.D.

Senior Research Associate, Salk Institute

hou@salk.edu

Title: Visualizing chromatin ultrastructure in interphase and mitotic cells by ChromEMT

Understanding how functions derive from structures have been my long term interest. I obtained my Ph.D. from UCSF, and studied the structural evolution of the p53 oligomerization domain in C.elegans and Drosophila by comparing both solution structures obtained by nuclear magnetic resonance. As a senior research associate in Clodagh O'Shea's lab at the Salk Institute, I first stumbled into the world of electron microscopy (EM) by using the genetically encoded EM probe miniSOG to visualize adenoviral nuclear polymer assembly in a cell nucleus, and later conceived ChromEMT in collaboration with Mark Ellisman's lab, to visualize 3D chromatin structures in a cell nucleus by multi-tilt EM tomography with an EM probe that can specifically label chromatin. My goal in the 4D nucleome is to link functions to the complex chromatin structures revealed by ChromEMT.

Click on the blue link - Join WebEx Meeting (above, not here) and you will be taken to a new window and asked to write your name and email - then click join. You might need to download the WebEx add on if you never used WebEx before. You will be taken to another window where you should choose call using computer (left circle) then you should be connected.

During Presentation:

ATTENDEES, PLEASE:

• MUTE YOUR COMPUTER MICROPHONE WHEN JOINING THE WEBINAR
• LET THE MODERATOR KNOW THAT YOU HAVE A QUESTION VIA CHAT
• QUESTIONS WILL BE ADDRESSED AT THE END OF EACH PRESENTATION, DURING THE DISCUSSION PERIODS.

In case we experience technical difficulties during the Webinars:

1. A new WebEx meeting invitation will be sent out immediately to the 4dn-network@4dnucleome.org email list.

2. If the problem with WebEx persists, OH will notify participants via 4dn-network@4dnucleome.org email to call 1.866.740.1260 and enter access code 8221626

3. Participants can find the Scientific Webinar slides presentations above under Scientific Webinar Series slides presentations.

When: January 26, 2018

Moderated by: Jennifer Phillips-Cremins

Member from Frank Alber's (contact), Lin Chen's group (Presenter and title will be determined by the group)

Member from Yijun Ruan's group

(Presenter and title will be determined by the group)