4D Nucleome Network Wiki

This is an old revision of the document!

December 2018

<ul><li>2018 4DN Annual Meeting and 4DN-ASCB Satellite Meeting concluded successfully!</li></ul>
<ul><li>New 4DN web portal launched! https://www.4dnucleome.org/</li></ul>

<ul><li>4DN wiki is under maintenance.</li></ul>

<ul><li>Job Opportunities: 6 job positions are still open. Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information.</li></ul>

<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a> by contacting nils@hms.harvard.edu or leonid@mit.edu. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>Stats by Dec 31, 2018</li>
<ul><li>Preprints (<a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>):  135 in total</li>
<li>Publications (<a href=“https://www.ncbi.nlm.nih.gov/sites/myncbi/1vMpf2j6i3bke/collections/50779401/public/”>Pubmed</a>):  170 in total.</li></ul>
<li>New preprints in December (<a href=“http://connect.biorxiv.org/relate/content/66” style=“background-color:transparent”>bioRxiv 4DN channel</a>):</li>
<ul><li>Mayank NK Choudhary, Ryan Z Friedman, Julia T Wang, Hyo Sik Jang, Xiaoyu Zhuo, Ting Wang. Co-opted transposons help perpetuate conserved higher-order chromosomal structures. doi: https://doi.org/10.1101/485342</li></ul>
<li>Recent new publications:</li>
<ul><li>Haifeng Wang, Xiaoshu Xu, Cindy M. Nguyen, Yanxia Liu, Yuchen Gao, Xueqiu Lin, Timothy Daley, Nathan H. Kipniss, Marie La Russa, Lei S. Qi. CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization. Cell. 2018 Nov 15;175(5):1405-1417.e14. doi: 10.1016/j.cell.2018.09.013.</li></ul></ul></ul>
<ul><li>Happy New Year 2019!</li></ul>

November 2018

<ul><li>2018 4DN Annual Meeting and 4DN-ASCB Satellite Meeting are coming next week (Dec 4-7). See you in San Diego</li></ul>

<ul><li>Upcoming workshops and conferences:</li>
<ul><li><a href=“https://www.grc.org/genome-architecture-in-cell-fate-and-disease-conference/2019/” style=“color:rgb(43,43,43)” target=“_blank”>2019 Gordon Research Conference -  </a><a href=“https://www.grc.org/genome-architecture-in-cell-fate-and-disease-conference/2019/” style=“background-color:transparent;font-size:19px;font-family:arial,sans-serif” target=“_blank”>The Eukaryotic Genome in 4 Dimensions: Integrative Approaches to Bridging Genotype and Phenotype</a></li>
<ul><li>When: August 4-9, 2019</li>
<li>Where: The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong</li>
<li>Chairs: Dave Gilbert and Yijun Ruan, Vice chairs: Victor Corces and Danny Leung</li></ul></ul></ul>
<ul><li>Job Opportunities: 6 job positions are still open. Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information.</li></ul>
<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a> by contacting nils@hms.harvard.edu or leonid@mit.edu. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>New preprints in November (<a href=“http://connect.biorxiv.org/relate/content/66” style=“background-color:transparent”>bioRxiv 4DN channel</a>):</li>
<ul><li>Zhangming Yan, Norman Huang, Weixin Wu, Weizhogn Chen, Yiqun Jiang, Jingyao Chen, Xuerui Huang, Xingzhao Wen, Jie Xu, Qiushi Jin, Kang Zhang, Zhen Chen, Shu Chien, Sheng Zhong. Genome-wide co-localization of RNA-DNA interactions and fusion RNA pairs. doi: <a href=“https://doi.org/10.1101/472019”>https://doi.org/10.1101/47201</a></li></ul></ul></ul>
<ul></ul>
<ul></ul>

October 2018

<ul><li>2018 4DN Annual Meeting registration has been closed on November 1st.</li></ul>
<ul><li>Upcoming workshops and conferences:</li>
<ul><li><a href=“https://www.grc.org/genome-architecture-in-cell-fate-and-disease-conference/2019/” style=“color:rgb(43,43,43)” target=“_blank”>2019 Gordon Research Conference -  </a><a href=“https://www.grc.org/genome-architecture-in-cell-fate-and-disease-conference/2019/” style=“background-color:transparent;font-size:19px;font-family:arial,sans-serif” target=“_blank”>The Eukaryotic Genome in 4 Dimensions: Integrative Approaches to Bridging Genotype and Phenotype</a></li>
<ul><li>When: August 4-9, 2019</li>
<li>Where: The Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong</li>
<li>Chairs: Dave Gilbert and Yijun Ruan, Vice chairs: Victor Corces and Danny Leung</li></ul></ul></ul>

<ul><li>Associate member applications approved (<a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/associate-membership-applications” style=“background-color:transparent” target=“_blank”>check here to know more</a>)</li>
<ul><li>Caterina Strambio</li>
<li>Peter Yingxiao Wang</li></ul></ul>

<ul><li>The Tier 2 cell line mESC G4 provided by University of Washington is available now. <a href=“https://www.4dnucleome.org/cell-lines.html” target=“_blank”>Click here to learn more.</a></li>
<ul></ul></ul>
<ul><li>Job Opportunities: 6 job positions are still open. Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information.</li></ul>

<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a> by contacting nils@hms.harvard.edu or leonid@mit.edu. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>Stats by Oct 30, 2018</li>
<ul><li>Preprints (<a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>):  113 in total</li>
<li>Publications (<a href=“https://www.ncbi.nlm.nih.gov/sites/myncbi/1vMpf2j6i3bke/collections/50779401/public/”>Pubmed</a>):  170 in total.</li></ul>
<li>Recent new publications:</li>
<ul><li>Jesse R. Dixon, Jie Xu, Vishnu Dileep, Ye Zhan, Fan Song, Victoria T. Le, Galip Gürkan Yardımcı, Abhijit Chakraborty, Darrin V. Bann, Yanli Wang, Royden Clark, Lijun Zhang, Hongbo Yang, Tingting Liu, Sriranga Iyyanki, Lin An, Christopher Pool, Takayo Sasaki, Juan Carlos Rivera-Mulia, Hakan Ozadam, Bryan R. Lajoie, Rajinder Kaul, Michael Buckley, Kristen Lee, Morgan Diegel, Dubravka Pezic, Christina Ernst, Suzana Hadjur, Duncan T. Odom, John A. Stamatoyannopoulos, James R. Broach, Ross C. Hardison, Ferhat Ay, William Stafford Noble, Job Dekker, David M. Gilbert & Feng Yue. Integrative detection and analysis of structural variation in cancer genomes. Nature Genetics. volume 50, pages1388–1398 (2018). doi: <a href=“https://doi.org/10.1038/s41588-018-0195-8”>https://doi.org/10.1038/s41588-018-0195-8</a></li></ul></ul></ul>
<ul><li>Scientific Webinar Series this Month: October 26, 2018</li></ul>

<ul>
<ul><li>
Presenter: Martin Falk (Massachusetts Institute of Technology) - “Heterochromatin drives organization of conventional and inverted nuclei” [<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDpmZGYxMmRjZGRlMjgxYjU” target=“_blank”>Link to presenter slides</a>]
</li>
<li>
Presenter: Andrew Barentine (Yale University) - “3D Nanoscopy of 10,000 Nuclei a Day“  [<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo3NmVmYWRmODgwYmE5MjJi” target=“_blank”>Link to presenter slides</a>]
</li></ul></ul>

</div>

September 2018

<ul><li style=“font-size:13.3333px”>November 1: Deadline for registration, abstract submission and hotel booking for the 2018 4DN Annual Meeting. </li>
<ul><li><a href=“http://4dn-annual-meetings.fluidreview.com/” style=“color:rgb(17,85,204)”>CLICK HERE TO REGISTER</a></li>
<li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2018-annual-meeting” style=“color:rgb(17,85,204)”>Click here to go the annual meeting wiki page for more information</a></li></ul></ul>
<ul><li>Job Opportunities: 6 job positions are still open. Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information.</li></ul>

<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a> by contacting nils@hms.harvard.edu or leonid@mit.edu. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>New preprints in September (<a href=“http://connect.biorxiv.org/relate/content/66” style=“font-size:medium”>bioRxiv 4DN channel</a>):</li>
<ul><li>Sadowski, M., Kraft, A., Szalaj, P., Wlasnowolski, M., Tang, Z., Ruan, Y., Plewczynski, D. Spatial Chromatin Architecture Alteration by Structural Variations in Human Genomes at Population Scale. doi: <a href=“https://doi.org/10.1101/266981”>https://doi.org/10.1101/266981</a> — Posted: 2018-09-14</li></ul>
<li>Recent new publications:</li>
<ul><li>James H. Sun, Linda Zhou, Daniel J. Emerson, Sai A. Phyo, Katelyn R. Titus, Wanfeng Gong, Thomas G. Gilgenast, Jonathan A. Beagan, Beverly L. Davidson, Flora Tasson, Jennifer E. Phillips-Cremins. Disease-Associated Short Tandem Repeats Co-localize with Chromatin Domain Boundaries. Cell. 2018 Sep 20;175(1):224-238.e15. doi:  <a href=“https://doi.org/10.1016/j.cell.2018.08.005”>https://doi.org/10.1016/j.cell.2018.08.005</a>. </li>
<li>Marc A. Marti-Renom, Genevieve Almouzni, Wendy A. Bickmore, Kerstin Bystricky, Giacomo Cavalli, Peter Fraser, Susan M. Gasser, Luca Giorgetti, Edith Heard, Mario Nicodemi, Marcelo Nollmann, Modesto Orozco, Ana Pombo & Maria-Elena Torres-Padilla. Challenges and guidelines toward 4D nucleome data and model standards. Nature Genetics. volume 50, pages1352–1358 (2018). <a href=“https://doi.org/10.1038/s41588-018-0236-3”>https://doi.org/10.1038/s41588-018-0236-3</a></li></ul></ul></ul>
<ul><li>Scientific Webinar Series this Month: September 28, 2018</li></ul>

<ul>
<ul><li>Presenter: Adrien Senecal (Albert Einstein College of Medicine) - The p53 transcription factor regulates transcriptional burst frequency and multiple steps of formation and disruption of chromatin on the p21 gene locus <a href=“https://www.google.com/url?q=https%3A%2F%2Fwww.dropbox.com%2Fs%2Fuj7ojiw6nr0hw57%2F2018-09-27%25204DN.pptx%3Fdl%3D0&sa=D&sntz=1&usg=AFQjCNHf6o9jxMapXCvp6IRSSRlTr81y_Q” target=“_blank”>[Link to presenter slides]</a></li></ul></ul>
<ul>
<ul><li>Presenter: Matthew Denholtz (University of California, San Diego) - Neutrophil genome dynamics in development and pathogen encounter <a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDpkMzk4NmI3MjA3OWEyOWQ” target=“_blank”>[Link to presenter slides]</a></li></ul></ul>

</div>

August 2018

<ul><li style=“font-size:13.3333px”>Register now for the 2018 4DN Annual Meeting (Dec 5-7, 2018). </li>
<ul style=“font-size:13.3333px”><li><a href=“http://4dn-annual-meetings.fluidreview.com/” style=“color:rgb(17,85,204)”>CLICK HERE TO REGISTER</a></li>
<li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2018-annual-meeting” style=“color:rgb(17,85,204)”>Click here to go the annual meeting wiki page for more information</a></li></ul></ul>
<ul><li>IHEC annual meeting registration (deadline Oct 15) and abstract submission (deadline Sept 26). You can find more information here: <a href=“http://ias.ust.hk/events/2018ihec/index.html”>http://ias.ust.hk/events/2018ihec/index.html</a></li></ul>
<ul><li>Job Opportunities: 8 job positions are still open. Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information. </li></ul>
<ul><li>Associate member applications approved (<a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/associate-membership-applications” target=“_blank”>check here to know more</a>)</li>
<ul><li>Maxwell Libbrecht and Michael Hoffman</li>
<li>Kai Tan</li></ul></ul>
<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a> by contacting nils@hms.harvard.edu or leonid@mit.edu. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>New preprints in August (<a href=“http://connect.biorxiv.org/relate/content/66” style=“font-size:medium”>bioRxiv 4DN channel</a>):</li>
<ul><li>Kim, S., Dunham, M., Shendure, J. A combination of transcription factors mediates inducible interchromosomal pairing. doi: <a href=“https://doi.org/10.1101/385047”>https://doi.org/10.1101/385047</a>. Posted: 2018-08-05</li></ul></ul></ul>
<ul>
<ul>
<ul><li>Rieger, B., Stallinga, S., Hulleman, C. N., Thorsen, R. O., Grunwald, D., Hammer, M. Photon count estimation in single-molecule localization microscopy. doi: <a href=“https://doi.org/10.1101/396424”>https://doi.org/10.1101/396424</a>. Posted: 2018-08-20</li></ul>
<li>Recent new publications:</li>
<ul><li>Peter Kerpedjiev, Nezar Abdennur, Fritz Lekschas, Chuck McCallum, Kasper Dinkla, Hendrik Strobelt, Jacob M. Luber, Scott B. Ouellette, Alaleh Azhir, Nikhil Kumar, Jeewon Hwang, Soohyun Lee, Burak H. Alver, Hanspeter Pfister, Leonid A. Mirny, Peter J. Park and Nils Gehlenborg. HiGlass: web-based visual exploration and analysis of genome interaction maps. Genome Biology. 2018, Aug 24;19(1):125. doi: <a href=“https://doi.org/10.1186/s13059-018-1486-1”>https://doi.org/10.1186/s13059-018-1486-1</a>.</li></ul></ul></ul>
<ul>
<ul>
<ul><li>Yu Chen, Yang Zhang, Yuchuan Wang, Liguo Zhang, Eva K. Brinkman, Stephen A. Adam, Robert Goldman, Bas van Steensel, Jian Ma, Andrew S. Belmont. Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler. Journal of Cell Biology. August 28, 2018. DOI: <a href=“https://doi.org/10.1083/jcb.201807108”>https://doi.org/10.1083/jcb.201807108</a></li></ul></ul></ul>
<ul>
<ul>
<ul><li>Won-Ki Cho, Jan-Hendrik Spille, Micca Hecht, Choongman Lee, Charles Li, Valentin Grube, Ibrahim I. Cisse. Mediator and RNA polymerase II clusters associate in transcription-dependent condensates. Science. 27 Jul 2018: Vol. 361, Issue 6400, pp. 412-415. doi: <a href=“https://doi.org/10.1126/science.aar4199”>https://doi.org/10.1126/science.aar4199</a></li></ul></ul></ul>
<ul>
<ul>
<ul><li>Shasha Chong, Claire Dugast-Darzacq, Zhe Liu, Peng Dong, Gina M. Dailey, Claudia Cattoglio, Alec Heckert, Sambashiva Banala, Luke Lavis, Xavier Darzacq, Robert Tjian. Imaging dynamic and selective low-complexity domain interactions that control gene transcription. Science  27 Jul 2018:Vol. 361, Issue 6400, eaar2555. doi: <a href=“https://doi.org/10.1126/science.aar2555”>https://doi.org/10.1126/science.aar2555</a></li></ul></ul></ul>
<ul>
<ul>
<ul><li>Hongtao Chen, Michal Levo, Lev Barinov, Miki Fujioka, James B. Jaynes & Thomas Gregor. Dynamic interplay between enhancer–promoter topology and gene activity. Nature Genetics. 2018 Volume 50, pages1296–1303.  doi: <a href=“https://doi.org/10.1038/s41588-018-0175-z”>https://doi.org/10.1038/s41588-018-0175-z</a></li></ul></ul></ul>
<ul>
<ul>
<ul><li>Sofia A. Quinodoz, Noah Ollikainen, Barbara Tabak, Ali Palla, Jan Marten Schmidt, Elizabeth Detmar, Mason M. Lai, Alexander A. Shishkin, Prashant Bhat, Yodai Takei, Vickie Trinh, Erik Aznauryan, Pamela Russell, Christine Cheng, Marko Jovanovic, Amy Chow, Long Cai, Patrick McDonel, Manuel Garber, Mitchell Guttman. Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus. Cell. 2018, Volume 174, Issue 3, 26, Pages 744-757.e24. doi: <a href=“https://doi.org/10.1016/j.cell.2018.05.024”>https://doi.org/10.1016/j.cell.2018.05.024 
</a></li></ul></ul></ul>
<ul><li>Scientific Webinar Series this Month: August 24, 2018</li></ul>

<ul>
<ul><li>Presenter: Roel Neijts (Institute Pasteur) - Exploring the TAD: specific enhancer-promoter interactions within regulatory domains <a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDoxMWEwYTk1OGI5ZTMwMjE” target=“_blank”>[Link to presenter slides]</a></li></ul></ul>
<ul>
<ul><li>Presenter: Arturas Petronis (Center for Addiction and Mental Health) - Spatiotemporal dynamics of chromatin: the circadian perspective <a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo0MWQ3NGRiYThhYTM0Mjg5” target=“_blank”>[Link to presenter slides]</a></li></ul>
<li> 
</li></ul>

</div>

July 2018

<ul><li style=“font-size:13.3333px”>Register now for the 2018 4DN Annual Meeting (Dec 5-7, 2018). </li>
<ul style=“font-size:13.3333px”><li><a href=“http://4dn-annual-meetings.fluidreview.com/” style=“color:rgb(17,85,204)”>CLICK HERE TO REGISTER</a></li>
<li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2018-annual-meeting” style=“color:rgb(17,85,204)”>Click here to go the annual meeting wiki page for more information</a></li></ul></ul>
<ul><li>IHEC annual meeting is now open for registration. You can find more information here: <a href=“http://ias.ust.hk/events/2018ihec/index.html”>http://ias.ust.hk/events/2018ihec/index.html</a></li></ul>
<ul><li>The NIH Common Fund 4D Nucleome program has released an <a href=“https://grants.nih.gov/grants/guide/notice-files/NOT-RM-18-017.html” style=“color:rgb(17,85,204)”>RFI</a> to solicit feedback from the national and international community on the remaining challenges towards a comprehensive analysis of the mammalian 4D Nucleome. Suggestions from all are welcome. Written responses must be submitted by August 6, 2018to <a href=“mailto:4DNucleome@mail.nih.gov”>4DNucleome@mail.nih.gov</a>. </li></ul>
<ul><li>Textbook seeks inputs and contributors. OH drafted a textbook titled <a href=“https://www.google.com/url?q=https%3A%2F%2Fzhonglab.gitbook.io%2F3dgenome%2F&sa=D&sntz=1&usg=AFQjCNHuVXB7qg8956XopTE8_QjxQL4coA”>3D Genome: from technology to visualization</a>, using an E-book format, with college students as the target audience. Please give comments and suggestions by emailing: <a href=“mailto:nucleomebook@4dnucleome.org” style=“font-size:large;background-color:transparent”>nucleomebook@4dnucleome.org</a>. Content contributors are welcome! 
 
</li>
<li>Job Opportunities: 8 job positions are open. Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information. </li></ul>
<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a> by contacting nils@hms.harvard.edu or leonid@mit.edu. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>New preprints in July:</li>
<ul><li>Mayuri Rege, Ji Hun Kim, Jacqueline Valeri, Margaret Dunagin, Aryeh Metzger, Wanfeng Gong, Jonathan Beagan, Arjun Raj,  Jennifer E Phillips-Cremins.LADL: Light-activated dynamic looping for endogenous gene expression control. doi: https://doi.org/10.1101/349340. Posted June 18, 2018.</li></ul>
<li>New publications in July:</li>
<ul><li> Xiaoyi Cao, Zhangming Yan, Qiuyang Wu, Alvin Zheng and Sheng Zhong. GIVE: portable genome browsers for personal websites. Genome Biology, 2018, 19:92. doi: <a href=“https://doi.org/10.1186/s13059-018-1465-6”>https://doi.org/10.1186/s13059-018-1465-6 </a></li></ul></ul></ul>
<ul><li><a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop”>4DN Youtube Channel</a> </li>
<ul><li>3 new videos released on the <a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop” style=“color:rgb(22,122,198);margin:0px;padding:0px;border:0px;background-image:initial;background-position:initial;background-repeat:initial;white-space:nowrap”>4D Nucleome Scientific Webinar Series</a> playlist.</li>
<ul><li><a href=“https://youtu.be/PC5v5axTSFs”>Elucidating the role of nascent RNA at enhancers</a></li>
<li><a href=“https://youtu.be/Q5nUrT_3xnk”>Interacting differentially methylated regions (iDMRs) to infer chromosome looping</a></li>
<li><a href=“https://youtu.be/qjTZWtLJ7Cg”>Trac-looping: a novel technique for analysis of chromatin accessibility and interaction</a></li></ul></ul></ul>
<ul><li>Scientific Webinar Series this Month: July 27, 2018</li></ul>
<ul>
<ul><li>Presenter: Tom Pastinen (McGill University) - Interacting differentially methylated regions (iDMRs) to infer chromosome looping</li></ul></ul>

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[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDozODg2YjA1M2E0MjI1YTcx”>Link to presenter slides</a>]<img src=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/newsletter/small_youtube_icon.png?attachauth=ANoY7cq-eNZq7SE8h4BXMOU8NJmcQ7cksyMGtpmyzYKcv6fldezFlwwc9BtzXFA5hqpmn-FhVApuVIWm8IoW8swhmCTV47obTBFXOUEKqjOPK5dBznlUGTcqd1B34zbtpBbZDR3HmnDCcOEQz-Kx1uHrJi6l9bqPTKE94BWGOSJHwJBniA7Q7xxsS1XpizDA8dtkQYVPxqnj2NQMo3hA291__aMT8Celf-cs_HolUnUxEHEsfhzaTPMJFOuVosG5A10O38sWqgpU&attredirects=1” style=“background-color:transparent;font-size:10pt”> <a href=“https://youtu.be/Q5nUrT_3xnk” style=“background-color:transparent”>https://youtu.be/Q5nUrT_3xnk</a>

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</blockquote>
</blockquote>

<ul>
<ul><li>Presenter: Keji Zhao (NHLBI) - Trac-looping: a novel technique for analysis of chromatin accessibility and interaction</li></ul></ul>

[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo3ZmIwM2ZlODlhODIxNg”>Link to presenter slides</a>]<img src=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/newsletter/small_youtube_icon.png?attachauth=ANoY7cq-eNZq7SE8h4BXMOU8NJmcQ7cksyMGtpmyzYKcv6fldezFlwwc9BtzXFA5hqpmn-FhVApuVIWm8IoW8swhmCTV47obTBFXOUEKqjOPK5dBznlUGTcqd1B34zbtpBbZDR3HmnDCcOEQz-Kx1uHrJi6l9bqPTKE94BWGOSJHwJBniA7Q7xxsS1XpizDA8dtkQYVPxqnj2NQMo3hA291__aMT8Celf-cs_HolUnUxEHEsfhzaTPMJFOuVosG5A10O38sWqgpU&attredirects=1” style=“background-color:transparent;font-size:10pt”> <a href=“https://youtu.be/qjTZWtLJ7Cg” style=“background-color:transparent”>https://youtu.be/qjTZWtLJ7Cg</a>

</blockquote>
</blockquote>
</blockquote>

June 2018

<ul><li style=“font-size:13.3333px”>Registration for the 2018 4DN Annual Meeting (Dec 5-7, 2018) is open now. </li>
<ul style=“font-size:13.3333px”><li><a href=“http://4dn-annual-meetings.fluidreview.com/” style=“color:rgb(17,85,204)”>CLICK HERE TO REGISTER</a></li>
<li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2018-annual-meeting” style=“color:rgb(17,85,204)”>Click here to go the annual meeting wiki page for more information</a></li></ul></ul>
<ul><li>Cell line WTC-11 has been moved from a Tier 2 to a Tier 1 cell line, as approved by the Cells WG. We now have 5 cell lines on Tier 1. Check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/working-groups-list/cell-lines-and-samples-wg”>cell line wiki page </a>for more details. </li></ul>
<ul><li>Upcoming workshops and conferences:</li>
<ul><li><a href=“https://www.grc.org/centromere-biology-conference/2018/”>Centromere Biology - 2018 Gordon Research Conference</a></li>
<ul><li>When: July 29 - August 3, 2018</li>
<li>Where: Mount Snow Resort, West Dover, Vermont, USA</li>
<li>Organizers: Aaron Straight and Sylvia Erhardt</li></ul></ul></ul>
<ul><li>Job Opportunities: Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement Page</a> for detailed information. </li>
<ul><li>2 new job opportunities: </li>
<ul><li>Bioinformatics Scientist – Harvard Medical School - DCIC (<a href=“http://dcic.4dnucleome.org/positions/scientist-02/”>Link to details</a>)</li>
<li>Senior Bioinformatics Scientist –  Harvard Medical School - DCIC (<a href=“http://dcic.4dnucleome.org/positions/scientist-03” style=“font-size:medium”>Link to details</a>)</li></ul>
<li>6 previous job opportunities are still open. </li></ul></ul>
<ul><li>4DN Publications: Please add your preprints into <a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>. Please also feel free to notify us of your new publications through email: OH@4dnucleome.org or twitter @4DNucleome. </li>
<ul><li>New preprints in June:</li>
<ul><li>Kim, J., Han, K. Y., Khanna, N., Ha, T., Belmont, A. S. Nuclear speckle fusion via long-range directional motion regulates the number and size of speckles. doi: <a href=“http://biorxiv.org/cgi/content/short/347955” style=“margin:0px;padding:0px;border:0px;outline:0px;vertical-align:baseline;font-style:inherit;font-variant:inherit;font-stretch:inherit;line-height:inherit;color:rgb(128,128,128)”>10.1101/34795</a>. Posted: 2018-06-15</li></ul>
<li>New publications in June: </li>
<ul><li>Ipek Tasan  Gabriela Sustackova  Liguo Zhang  Jiah Kim  Mayandi Sivaguru Mohammad HamediRad  Yuchuan Wang  Justin Genova  Jian Ma  Andrew S Belmont, Huimin Zhao. CRISPR/Cas9-mediated knock-in of an optimized TetO repeat for live cell imaging of endogenous loci. Nucleic Acids Research, Published: 15 June 2018. doi: <a href=“https://doi.org/10.1093/nar/gky501”>https://doi.org/10.1093/nar/gky501</a></li>
<li>Ji Hun Kim, Katelyn R.Titus, Wanfeng Gong, Jonathan A. Beagan, Zhendong Cao, Jennifer E.Phillips-Cremins. 5C-ID: Increased resolution Chromosome-Conformation-Capture-Carbon-Copy with in situ 3C and double alternating primer design. Methods, Volume 142, 1 June 2018, Pages 39-46. doi: <a href=“https://doi.org/10.1016/j.ymeth.2018.05.005”>https://doi.org/10.1016/j.ymeth.2018.05.005</a></li>
<li>Yang Yang, Quanquan Gu, Yang Zhang, Takayo Sasaki, Julianna Crivello, Rachel J. O'Neill, David M. Gilbert, Jian Ma. Continuous-Trait Probabilistic Model for Comparing Multi-species Functional Genomic Data. Cell Systems. Published Online: June 20, 2018. doi: <a href=“https://doi.org/10.1016/j.cels.2018.05.022” style=“color:rgb(28,150,211);font-family:arial,sans-serif”>https://doi.org/10.1016/j.cels.2018.05.022</a></li>
<li>Weizhong Chen, Zhangming Yan, Simin Li, Norman Huang, Xuerui Huang, Jin Zhang, Sheng Zhong. RNAs as Proximity-Labeling Media for Identifying Nuclear Speckle Positions Relative to the Genome. iScience. Volume 4, p204–215, 29 June 2018. doi: <a href=“https://doi.org/10.1016/j.isci.2018.06.005” style=“background-color:transparent;font-family:arial,sans-serif;font-size:medium”>https://doi.org/10.1016/j.isci.2018.06.005</a></li>
<li>Ruochi Zhang  Yuchuan Wang  Yang Yang  Yang Zhang  Jian Ma. Predicting CTCF-mediated chromatin loops using CTCF-MP. Bioinformatics, Volume 34, Issue 13, 1 July 2018, Pages i133–i141. doi: <a href=“https://doi.org/10.1093/bioinformatics/bty248” style=“color:rgb(0,111,183);margin:0px;padding:0px;border:0px;font-stretch:inherit;line-height:inherit;vertical-align:baseline;word-wrap:break-word;word-break:break-word”>https://doi.org/10.1093/bioinformatics/bty248</a></li></ul></ul></ul>

<ul><li>Scientific Webinar Series this Month: June 22, 2018</li></ul>
<ul>
<ul><li>Presenter: Nicola Neretti (Brown University) - Inference and Validation of Chromosomes' 3D Structure 
</li></ul></ul>

[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDoxNTMyYjc4NzY4Nzc5MTZk”>Link to presenter slides</a>]

</blockquote>
</blockquote>
</blockquote>

<ul>
<ul><li>Presenter: Andrew Field (Harvard Medical School) -  Elucidating the role of nascent RNA at enhancers</li></ul></ul>

[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDoyNGFkODM5NTcwNzg5NDgz”>Link to presenter slides</a>] <img src=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/newsletter/small_youtube_icon.png?attachauth=ANoY7cq-eNZq7SE8h4BXMOU8NJmcQ7cksyMGtpmyzYKcv6fldezFlwwc9BtzXFA5hqpmn-FhVApuVIWm8IoW8swhmCTV47obTBFXOUEKqjOPK5dBznlUGTcqd1B34zbtpBbZDR3HmnDCcOEQz-Kx1uHrJi6l9bqPTKE94BWGOSJHwJBniA7Q7xxsS1XpizDA8dtkQYVPxqnj2NQMo3hA291__aMT8Celf-cs_HolUnUxEHEsfhzaTPMJFOuVosG5A10O38sWqgpU&attredirects=1” style=“background-color:transparent;font-size:10pt”> <a href=“https://youtu.be/PC5v5axTSFs” style=“background-color:transparent;font-size:10pt”>https://youtu.be/PC5v5axTSFs</a>

\\

</blockquote>
</blockquote>
</blockquote>

May 2018

<ul><li style=“font-size:13.3333px”>Registration for the 2018 4DN Annual Meeting (Dec 5-7, 2018) is open. </li>
<ul style=“font-size:13.3333px”><li><a href=“http://4dn-annual-meetings.fluidreview.com/” style=“color:rgb(17,85,204)”>CLICK HERE TO REGISTER</a></li>
<li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2018-annual-meeting” style=“color:rgb(17,85,204)”>Click here to go the Annual Meeting wiki page for more information</a></li></ul></ul>
<ul><li>Upcoming workshops and conferences:</li>
<ul><li><a href=“https://www.grc.org/centromere-biology-conference/2018/”>Centromere Biology - 2018 Gordon Research Conference</a></li>
<ul><li>When: July 29 - August 3, 2018</li>
<li>Where: Mount Snow Resort, West Dover, Vermont, USA</li>
<li>Organizers: Aaron Straight and Sylvia Erhardt</li></ul></ul></ul>

<ul><li>Job Opportunities: Please check the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement page</a> for detail information. </li>
<ul><li>1 new job opportunity: </li>
<ul><li>Postdoc positions (multiple, including NIH-funded Nucleomics project) – California Institute of Technology (<a href=“http://ismagilovlab.caltech.edu/positions/index.shtml”>Link to detail</a>)</li></ul>
<li>5 previous job opportunities are still open. </li></ul></ul>

<ul><li>4DN Publications</li>
<ul><li>Stats by May 31, 2018</li>
<ul><li>Preprints (<a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>): 108 in total</li>
<li>Publications (<a href=“https://www.ncbi.nlm.nih.gov/sites/myncbi/1vMpf2j6i3bke/collections/50779401/public/”>Pubmed</a>):  157 in total, 2 new publications in May</li></ul>
<li>New publications in May: </li>
<ul><li>Rivera-Mulia JC, Dimond A, Vera D, Trevilla-Garcia C, Sasaki T, Zimmerman J, Dupont C, Gribnau J, Fraser P, Gilbert DM. Allele-specific control of replication timing and genome organization during development. Genome Res. 2018 May 7 [Epub ahead of print]. <a href=“https://genome.cshlp.org/content/early/2018/05/07/gr.232561.117.long”>doi: 10.1101/gr.232561.117</a></li>
<li>Marchal C, Sasaki T, Vera D, Wilson K, Sima J, Rivera-Mulia JC, Trevilla-García C, Nogues C, Nafie E, Gilbert DM. Genome-wide analysis of replication timing by next-generation sequencing with E/L Repli-seq.Nat Protoc. 2018 May;13(5):819-839.<a href=“https://www.nature.com/articles/nprot.2017.148”> doi: 10.1038/nprot.2017.148</a></li></ul></ul></ul>
<ul><li><a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop”>4DN Youtube Channel</a> </li>
<ul><li>3 new videos released on the <a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop” style=“margin:0px;padding:0px;border:0px;background-image:initial;background-position:initial;background-repeat:initial;color:rgb(22,122,198);white-space:nowrap”>4D Nucleome Scientific Webinar Series</a> playlist.</li>
<ul><li><a href=“https://www.youtube.com/watch?v=rhQu9-as16Y”>CUT&RUN: Efficient genome-wide profiling of the epigenomic landscape </a></li>
<li><a href=“https://youtu.be/PFskL_9TfI4”>Looking beyond pairwise 3D conformation of the genome by MC-4C</a></li>
<li><a href=“https://youtu.be/vzy4WbU5Y5Q”>How the Genome Awakens in Zebrafish</a></li></ul></ul></ul>
<ul><li>Scientific Webinar Series this Month: May 25, 2018</li>
<ul><li>Presenter: Amin Allahyar (Hubrecht Institute) - Looking beyond pairwise 3D conformation of the genome by MC-4C HD</li></ul></ul>

<blockquote style=“margin:0 0 0 40px;border:none;padding:0px”>
<blockquote style=“margin:0 0 0 40px;border:none;padding:0px”>
<blockquote style=“margin:0 0 0 40px;border:none;padding:0px”><a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo3MDI5NjBhNmViMDVkNDY5”>[Link to presenter slides]</a>   <img src=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/newsletter/small_youtube_icon.png?attachauth=ANoY7cq-eNZq7SE8h4BXMOU8NJmcQ7cksyMGtpmyzYKcv6fldezFlwwc9BtzXFA5hqpmn-FhVApuVIWm8IoW8swhmCTV47obTBFXOUEKqjOPK5dBznlUGTcqd1B34zbtpBbZDR3HmnDCcOEQz-Kx1uHrJi6l9bqPTKE94BWGOSJHwJBniA7Q7xxsS1XpizDA8dtkQYVPxqnj2NQMo3hA291__aMT8Celf-cs_HolUnUxEHEsfhzaTPMJFOuVosG5A10O38sWqgpU&attredirects=1” style=“background-color:transparent;font-size:10pt”> <a href=“https://youtu.be/PFskL_9TfI4” style=“background-color:transparent;font-size:10pt”>https://youtu.be/PFskL_9TfI4</a></blockquote>
</blockquote>
</blockquote>

<ul>
<ul><li>Presenter: Brad Cairns (University of Utah) and Antonio Giraldez (Yale University) -  How the Genome Awakens in Zebrafish</li></ul></ul>

<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo1ZWM0YWRkNTkzNmRlOTcy”>[Link to presenter slides]</a>   <img src=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/newsletter/small_youtube_icon.png?attachauth=ANoY7cq-eNZq7SE8h4BXMOU8NJmcQ7cksyMGtpmyzYKcv6fldezFlwwc9BtzXFA5hqpmn-FhVApuVIWm8IoW8swhmCTV47obTBFXOUEKqjOPK5dBznlUGTcqd1B34zbtpBbZDR3HmnDCcOEQz-Kx1uHrJi6l9bqPTKE94BWGOSJHwJBniA7Q7xxsS1XpizDA8dtkQYVPxqnj2NQMo3hA291__aMT8Celf-cs_HolUnUxEHEsfhzaTPMJFOuVosG5A10O38sWqgpU&attredirects=1” style=“background-color:transparent;font-size:10pt”> <a href=“https://youtu.be/vzy4WbU5Y5Q” style=“background-color:transparent;font-size:10pt”>https://youtu.be/vzy4WbU5Y5Q</a>

</blockquote>
</blockquote>
</blockquote>

\\

April 2018

<ul style=“font-size:13.3333px”><li>Registration for the 2018 4DN Annual Meeting (Dec 5-7, 2018) is open now. </li>
<ul><li><a href=“http://4dn-annual-meetings.fluidreview.com/” style=“color:rgb(17,85,204)”>CLICK HERE TO REGISTER</a></li>
<li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2018-annual-meeting” style=“color:rgb(17,85,204)”>Click here to the annual meeting wiki page for more information</a></li></ul></ul>
<ul><li>Announcing <a href=“https://groups.google.com/a/4dnucleome.org/forum/#!forum/4dn-cell-eng”>4DN Cell Engineering Discussion Group</a>, a forum for making and sharing new engineered cell lines. </li></ul>
<ul style=“font-size:13.3333px”><li>Announcing <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/collaboration-plaza”>Collaboration plaza</a>, a new wiki page for seeking collaboration opportunities within the 4DN network. </li></ul>
<ul><li>Job Opportunities: 5 job opportunities are still open. Please check detail information on <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement page</a>.</li></ul>
<ul style=“font-size:13.3333px”></ul>

<ul><li style=“font-size:13.3333px”>4DN Publications</li>
<ul><li>Stats by Apr 30, 2018</li>
<ul><li>Preprints (<a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>):  108 in total, 3 new preprints in April</li>
<li>Publications (<a href=“https://www.ncbi.nlm.nih.gov/sites/myncbi/1vMpf2j6i3bke/collections/50779401/public/”>Pubmed</a>):  156 in total.</li></ul>
<li style=“font-size:13.3333px”>New preprints in April:</li>
<ul><li>RNAs as proximity labeling media for identifying nuclear speckle positions relative to the genome. Weizhong Chen, Zhangming Yan, Simin Li, Norman Huang, Xuerui Huang, Jin Zhang, Sheng Zhong. doi: <a href=“https://doi.org/10.1101/300483”>https://doi.org/10.1101/300483</a></li>
<li>Pattern-Driven Navigation in 2D Multiscale Visual Spaces with Scalable Insets. Fritz Lekschas,  Michael Behrisch,  Benjamin Bach,  Peter Kerpedjiev,  Nils Gehlenborg,  Hanspeter Pfister. doi: <a href=“https://doi.org/10.1101/301036”>https://doi.org/10.1101/301036</a></li>
<li>TSA-Seq Mapping of Nuclear Genome Organization. Yu Chen, Yang Zhang, Yuchuan Wang, Liguo Zhang, Eva K. Brinkman, Stephen A. Adam, Robert Goldman, Bas van Steensel, Jian Ma, Andrew S. Belmont. doi: <a href=“https://doi.org/10.1101/307892”>https://doi.org/10.1101/307892</a></li></ul></ul></ul>
<ul><li>Scientific Webinar Series this Month:</li></ul>
<ul>

April 27, 2018

<ul>
Presenter:  Karla Neugebauer (Yale University) - The Cell Nucleus under Stress
[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDozNjY3NGFmNzkyNGE0ODFl”>Link to presenter slides</a>]
Presenter:  Steve Henikoff (Fred Hutchinson Cancer Research Center) - CUT&RUN: Efficient genome-wide profiling of the epigenomic landscape 
[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDozNjMyZjQzMWU0M2YyMmQ1”>Link to presenter slides</a>]</ul></ul>
<ul>
<ul>
<ul> \\</ul>
</ul></ul>

March 2018

<ul><li>Announcing <a href=“https://groups.google.com/a/4dnucleome.org/forum/#!forum/4dn-cell-eng”>4DN Cell Engineering Discussion Group</a>, a forum for making and sharing new engineered cell lines. </li></ul>
<ul><li>Announcing <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/collaboration-plaza”>Collaboration plaza</a>, a new wiki page for seeking collaboration opportunities within the 4DN network. </li></ul>
<ul><li>New Job Opportunities: Check detail information on <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities” style=“background-color:transparent”>4DN Job Advertisement page </a></li></ul>
<ul>
<ol><li>Senior Computational Biologist – The Florida State University (FSU) Center for Genomics (CGPM)</li>
<li>Computational biology postdoc position to analyze chromatin architecture in cancer – Jane Skok and Richard Bonneau New York University School of Medicine and NYU Data Sciences</li>
<li>Postdoc position to study chromatin architecture in cancer: experience in chromosome conformation and capture AND CRISPR preferred – Jane Skok and New York University School of Medicine</li>
<li>Postdoc position to study dynamic chromatin architecture and transcription in developmental systems – Thomas Gregor, Princeton University (USA) and Institut Pasteur (France)</li>
<li>Assistant in Research (12 month salaried, Molecular Biology) – Florida State University Department of Biological Science Core Facility</li>
</ol></ul>
<ul><li>4DN Publications</li>
<ul><li>Stats by Mar 31, 2018</li>
<ul><li>Preprints (<a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>):  105 in total.</li>
<li>Publications (<a href=“https://www.ncbi.nlm.nih.gov/sites/myncbi/1vMpf2j6i3bke/collections/50779401/public/”>Pubmed</a>):  156 in total. 1 new publication in March, 2018. </li></ul>
<li>Recent publication highlights:</li>
<ul><li>J. H. Gibcus, K.Samejima, L. Goloborodko, I. Samejima, N. Naumova, J. Nuebler, M. T. Kanemaki, L. Xie, J. R. Paulson, W. C. Earnshaw, L. A. Mirny, J. Dekker, <a href=“http://science.sciencemag.org/content/359/6376/eaao6135.long”>A pathway for mitotic chromosome formation</a>. Science 359, eaao6135 (2018).</li>
<li>M. Ganji, I. A.Shaltiel, S. Bisht, E. Kim, A. Kalichava, C. H. Haering, C. Dekker. <a href=“http://science.sciencemag.org/content/early/2018/02/21/science.aar7831.full”>Real-time imaging of DNA loop extrusion by condensing</a>. Science 359, eaar7831(2018). </li></ul></ul></ul>
<ul></ul>
<ul><li><a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop”>4DN Youtube Channel</a> released two new videos from Scientific Webinar Series (Feb 23, 2018).</li>
<ul><li><a href=“https://www.youtube.com/watch?v=8h4xF77wfb8&list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop&index=2&t=0s”>Paul Fields (University of Washington) - Dynamics of Genome Reorganization during Human Cardiogenesis </a></li>
<li><a href=“https://www.youtube.com/watch?v=m4OC3kWfqOk&list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop&index=1&t=0s”>Caroline Bartman (University of Pennsylvania) - Frequency modulation of polymerase recruitment via transcriptional bursting is a dominant mode of transcriptional regulation </a></li></ul></ul>
<ul></ul>
<ul><li>Scientific Webinar Series this Month:</li></ul>
<ul>

March 23, 2018

<ul>
Presenter:  Rajarshi P Ghosh (Stanford University) - Chromatin dynamics: Motional signatures of transcriptional state 
<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDoxMzE0MjQxMjM5MmU3ODNj”>[Link to presenter slides]</a></ul></ul>

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February 2018

<ul><li><a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/job-opportunities”>Job advertisement page</a> is created on 4DN wiki. Welcome to post job advertisement!</li></ul>
<ul><li>4DN Scientific Webinar Series videos are on<a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop”> </a><a href=“https://www.youtube.com/playlist?list=PLiJ0I11RAJ2rPJHImnuFiQJg7P1qsBhop”>4DN Youtube Channel</a> now. </li></ul>
<ul><li>Scientific Webinar Series this Month: The videos of the two presentations will be released on<a href=“goog_672507352”> </a>4DN Youtube Channel. </li>

February 23, 2018

<ul style=“font-size:large”>
Presenter:  Paul Fields (University of Washington) - Dynamics of Genome Reorganization during Human Cardiogenesis 
[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDoxOWFhNTQxNTJlNWIyOTVh”>Link to presenter slides</a>]
Presenter:  Caroline Bartman (University of Pennsylvania) - Frequency modulation of polymerase recruitment via transcriptional bursting is a dominant mode of transcriptional regulation 
[<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDozYTg4NGQ4YmI4Njg4MDc0”>Link to presenter slides</a>] \\</ul></ul>
<ul><li>4DN Publications</li>
<ul><li>Stats by Feb 28, 2018</li>
<ul><li>Preprints (<a href=“http://connect.biorxiv.org/relate/content/66”>bioRxiv 4DN channel</a>):  105 in total, 64 out of them unpublished. 5 new preprints in Feb 2018.</li>
<li>Publications (<a href=“https://www.ncbi.nlm.nih.gov/sites/myncbi/1vMpf2j6i3bke/collections/50779401/public/”>Pubmed</a>): 155 in total. </li></ul>
<ul></ul></ul></ul>
<ul></ul>
<ul></ul>
<ul><li>Job Opportunities:</li>
<ul><li>
<table border=“1” cellpadding=“0” cellspacing=“0” dir=“ltr” style=“table-layout:fixed;font-size:10pt;font-family:arial,sans,sans-serif;width:0px;border-collapse:collapse;border:none”>
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<tbody>
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<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”></td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Position/Title</td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Employer</td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Job Type</td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Post Date</td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Deadline</td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Status</td>
<td style=“overflow:hidden;padding:2px 3px 2px 3px;vertical-align:middle;background-color:#3c78d8”>Apply methods / contacts</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;background-color:rgb(60,120,216);font-weight:bold;word-wrap:break-word;color:rgb(255,255,0)”>Detail Link</td>
</tr>
<tr style=“height:21px”>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word;text-align:center”>1</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word”>Senior Computational Biologist</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word”>The Florida State University (FSU) Center for Genomics (CGPM)</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;font-family:sans-serif;font-size:9pt;word-wrap:break-word”>Full-time non-tenure-track</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word”>Feb 10, 2018</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word”>NA</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word”>Open</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word”>Online apply</td>
<td style=“overflow:hidden;padding:2px 3px;vertical-align:middle;word-wrap:break-word;color:rgb(17,85,204)”><a href=“https://www.indeed.com/m/viewjob?jk=02054377ee0aec74&from=serp&prevUrl=https://www.indeed.com/m/jobs?q=Computational+biologist&l=Tallahassee%2C+FL”>Indeed</a></td>
</tr>
</tbody>
</table>
</li></ul></ul>
<ul></ul>
<ul></ul>

January 2018

<ul><li>4DN Program Announces Associate Membership. Read the <a href=“https://commonfund.nih.gov/sites/default/files/4DN%20Associate%20Membership.pdf”>PDF file</a> for more information.</li></ul>
<ul><li>Scientific Webinar Series this Month: </li>

January 26, 2018

Presenter:  Yi Kou (University of Southern California) - Mapping genome 3D structure by direct DNA-DNA photo-crosslinking and click enrichment
Presenter:  Paul Olivier (University of Toronto) - Developing a new framework to detect and link protein complexes to specific chromatin interactions
Presenter: Meizhen Zheng (The Jackson Laboratory of Genomic Medicine) - Multiplex Chromatin Interaction Analysis with Single Molecule Precision

</ul>
<ul> 
</ul>
</ul>

December 2017

<ul><li>The 4DN Data Release and Use Policy has been approved and released (check it on <a href=“https://www.4dnucleome.org/policies.html”>4DN web portal</a>)</li></ul>
<ul><li> 
</li></ul>

November 2017

<ul><li>Outreach and in-reach slides: OH prepared slides for any consortium members to change and use for 4DN outreach and in-reach activities</li>
<ul><li><a href=“https://docs.google.com/a/eng.ucsd.edu/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo3MzE2YmE5ZWI3OTUxNmM5” style=“font-family:arial,sans-serif”>Outreach slides</a></li>
<li><a href=“https://docs.google.com/a/eng.ucsd.edu/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo3Mzg5NGIyM2UwYmIyZWY” style=“font-family:arial,sans-serif”>In-reach slides</a></li></ul></ul>

The first education video produced by 4DN has been released on YouTube. <a href=“https://www.youtube.com/watch?v=YVv3i42JFWg”>4DN Imaging Workshop: Toward Microscopy Standardization</a>

</li>
<ul><li>Thanks to Dr. Grunwald for authorizing OH to make the video.</li>
<li>Welcome to contact OH to submit or recommend 4DN related education and outreach videos.</li></ul></ul>

<ul><li>Release of <a href=“https://www.google.com/url?q=https%3A%2F%2Fwww.4dnucleome.org%2Fcell-lines.html&sa=D&sntz=1&usg=AFQjCNFSd5meFjxxClQbRdf2vuQwv3IF9w”>cell line SOP on 4DN web portal</a>. Click on each cell line to access the SOPs and other information.</li></ul>
<ul style=“font-size:13.3333px”><li> 
</li></ul>

October 2017

<a href=“https://docs.google.com/document/d/12wyR5BxbngARaPzw2ckBi0Ws33keZTr9f8yb6HiSyH0/edit”>2017 4DN Annual Meeting Report. </a>

</li></ul>

<a href=“https://docs.google.com/a/4dnucleome.org/viewer?a=v&pid=sites&srcid=NGRudWNsZW9tZS5vcmd8NGQtbnVjbGVvbWUtd2lraXxneDo4M2RiN2ViZjYzZWJmMDc”>2017 4DN Annual Meeting survey results</a>. Thanks for your feedback.

</li></ul>

<a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/working-groups-list/imaging-data-standards-wg/microscope-calibration-project”>Microscope Calibration Project</a>: a new joint project in Imaging Data Standards and Joint Analysis working group

</li></ul>
<ul style=“font-size:13.3333px”><li>

Scientific Webinar Series this Month: 

</li></ul>

<ul>

October 27, 2017

Presenter: Adan Horta (Columbia University) - Interchromosomal Interactions as a Source of Neuronal Diversity

Presenter: Horng Ou (Salk Institute) -  Visualizing chromatin ultrastructure in interphase and mitotic cells by ChromEMT

</ul>

September 2017

2017 4DN Annual Meeting was successfully held in Bethesda on September 17 - 20

</li></ul>
<ul><li>

Please complete the <a href=“https://docs.google.com/forms/d/e/1FAIpQLSfQszioZiYLXZdKzm1ghWoJRNdXHm8rDA8-F-TzieAIjtXZlg/viewform”>2017 4DN Annual Meeting Survey</a> before Oct 12. Your feedbacks are greatly appreciated!

</li></ul>
<ul><li style=“color:rgb(51,51,51);font-weight:bold”>

A quick guide to 4DN visualization software: <a href=“https://www.nature.com/news/plot-a-course-through-the-genome-1.22553” style=“font-weight:normal”>Plot a course through the genome</a>

</li></ul>

The 4D Nucleome perspective paper published in Nature: <a href=“http://www.nature.com/nature/journal/v549/n7671/full/nature23884.html”>The 4D nucleome project</a>

</li>
<ul style=“font-size:13.3333px”></ul></ul>

August 2017

2017 4DN Annual Meeting is coming on September 17 - 20:

</li>
<ul><li>Registration and abstract submission ended on August 15</li>
<ul><li>278 members registered</li>
<li>128 abstracts submitted</li></ul></ul></ul>
<ul style=“color:rgb(34,34,34);font-family:arial,sans-serif;font-size:large”><li style=“font-size:13.3333px”>

4DN Opportunity Pool Initiative announces <a href=“https://www.4dnucleome.org/tcpa.html” style=“font-family:arial”>2017 Transformative Collaborative Project Awards</a>

\\</li></ul>
<ul style=“font-size:13.3333px”></ul>

<ul></ul>

<ul style=“font-size:13.3333px”>

<ul>

</ul>

</ul>
<ul><li style=“font-size:13.3333px”>

The EFMA office will be holding an informational webinar on the EFRI FY2018 solicitation on September 7th, 2017, 1 p.m. Eastern Daylight Time

\\</li>
<ul><li>

The topics of the <a href=“https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=13708” style=“color:rgb(17,85,204);font-weight:normal”>FY18 EFRI solicitation</a> are:

\\</li>
<ul><li>Chromatin and Epigenetic Engineering (CEE)</li>
<li>Continuum, Compliant, and Configurable Soft Robotics Engineering (C3 SoRo)</li></ul>
<li>Registration details for the webinar are available <a href=“https://www.nsf.gov/events/event_summ.jsp?cntn_id=242816” style=“color:rgb(17,85,204)”>here</a>.</li></ul></ul>

Scientific Webinar Series this Month: 

</li>

<ul>

August 25, 2017

Presenter: Kit S. Lam  (University of California Davis) - The use of OBOC combinatorial library method to discover Genetically Encoded Small            Illuminants for cellular imaging

Presenter: Suhas Rao (Stanford University) - Tracking the 4D nucleome during cohesin loss and recovery

</ul>

</ul>
<ul>
<ul style=“font-size:13.3333px”></ul></ul>
<ul style=“font-size:13.3333px”>
<ul></ul>
<ul></ul></ul>

July 2017

<ul style=“font-size:13.3333px”><li>Reminder: Last 2 weeks for registration of 2017 Annual Meeting </li>
<ul><li>Registration deadline is August 15, 2017. Register here:  <a href=“https://4dn-annual-meetings.fluidreview.com/”>https://4dn-annual-meetings.fluidreview.com </a></li>
<li>Abstract and poster submission deadline is also August 15, 2017.</li>
<li>Check more information about abstract submission, poster submission, and hotel booking on the wiki page: <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting”>https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting</a></li></ul></ul>
<ul><li>Invitation: WORKSHOP (EXTRA SESSION FOLLOWING THE 2017 4DN MEETING)</li>
<ul><li>Topic: Integrated Approaches for Spatial and Temporal Mapping of Gene Activity in Cells and Tissues</li>
<li>Time: 1:00 to 5:00 PM, Sept 20, 2017</li>
<li>Location: Conference Room B, Neuroscience Center, 6001 Executive Blvd</li>
<li>Session Chairs: Rob Singer, Joan Ritland and Richard Conroy</li></ul></ul>
<ul><li style=“font-size:13.3333px”>ISMB Tutorial: 3D Genome Data Processing, Analysis, and Visualization Tutorial</li>
<ul><li><a href=“https://github.com/hms-dbmi/3d-genome-processing-tutorial”>https://github.com/hms-dbmi/3d-genome-processing-tutorial</a></li></ul></ul>
<ul><li style=“color:rgb(51,51,51);font-weight:bold”>

Scientific Webinar Series this Month: 

</li>

<ul>

July 28, 2017

Presenter: Rupesh Amin (Juno Therapeutics) - Engineering a Tethering System to Dissect Gene Regulation in Mouse Embryonic Stem Cells

Presenter: Maximiliaan Huisman (University of Massachusetts Medical School) - Cryo-FM: moving towards single-basepair resolution in fluorescence microscopy

</ul>

June 2017

<ul><li>Reminder of 2017 Annual Meeting registration</li>
<ul><li>Registration deadline is August 15, 2017. Register here:  <a href=“https://4dn-annual-meetings.fluidreview.com”>https://4dn-annual-meetings.fluidreview.com </a></li>
<li>Abstract and poster submission deadline is August 15, 2017.</li>
<li>Check more information about abstract submission, poster submission, and hotel booking on the wiki page: <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting”>https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting</a></li></ul></ul>
<ul style=“font-size:13.3333px”><li>New Upcoming Education and Outreach Event</li>
<ul><li><a href=“http://www.google.com/url?q=http%3A%2F%2Fwww.keystonesymposia.org%2Findex.cfm%3Fe%3Dweb.Meeting.Program%26meetingid%3D1542&sa=D&sntz=1&usg=AFQjCNFJnsrrZPpnZICih4dQ-LEzPNDY0g”>Chromatin Architecture and Chromosome Organization</a> (March 23 - 27, 2018)</li>
<ul><li>Scientific Organizers: Edith Heard and Peter Fraser</li>
<li>Location: Whistler, British Columbia, Canada </li></ul></ul></ul>
<ul><li style=“color:rgb(51,51,51);font-size:14.6667px;font-weight:bold”>

Scientific Webinar Series this Month: 

</li>

<ul>

June 23, 2017

Presenter: Cory Lindsay (Scripps Research Institute) - Analysis of the nuclear lamina by proteomics and proximity labeling

Presenter: Takashi Fukaya (Princeton University) - Visualization of trans-homologue enhancer-promoter interaction in living Drosophila embryos

</ul>

</ul>
<h4>

</h4>
<h4>
<ul></ul>
</h4>

May 2017

<h4>
<ul><li style=“font-size:13.3333px”>2017 4D Nucleome Annual Meeting</li>
<ul><li style=“font-size:13.3333px”>Registration opens and the deadline is August 15, 2017. Register here:  <a href=“https://4dn-annual-meetings.fluidreview.com”>https://4dn-annual-meetings.fluidreview.com </a></li>
<li>Check more information about abstract submission, poster submission, and hotel booking on the wiki page: <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting”>https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting</a></li></ul></ul>
</h4>
<h4>
<ul><li>4DN Investigator Featured on “Science Happens!”  Watch Dr. Job Dekker describe how the folding of DNA strands holds cues to human health <a href=“https://www.statnews.com/2016/03/31/dna-shape-double-helix-dekker/”>here</a>.</li></ul>

</h4>
<h4>
<ul><li>Conversations: A Guide to Packing Your DNA. Cell editor Marta Koch and the 4D Nucleome grantees Drs. Job Dekker, Mitchell Guttman, and Stavros Lomvardas discuss the organization of genetic material in the nucleus, how it occurs, and why it matters. Find it <a href=“http://www.sciencedirect.com/science/article/pii/S0092867416303373”>here</a>.</li></ul>
</h4>
<h4>
<ul><li>

Scientific Webinar Series this Month: 

</li>

<ul>

May 26, 2017

Presenter: Vishnu Dileep (Florida State University) - Measuring genome-wide replication timing in single cells

Presenter: Yaniv Lubling (Weizmann Institute of Science, Israel) - Cell cycle dynamics of chromosomal organization at single-cell resolution

</ul>

</ul>
</h4>
<h4 style=“font-size:13.3333px”>
<ul><li> 
</li></ul>
</h4>

April 2017

<h4>
<ul><li>2017 4D Nucleome Annual Meeting</li>
<ul><li>Dates:           Sept 17 - 20, 2017</li>
<li>Location:       Bethesda North Marriott Hotel & Conference Center, 5701 Marinelli Road North Bethesda, Maryland 20852, USA</li>
<li>The 2017 4D Nucleome Annual Meeting is a closed meeting for the 4DN funded PIs and associates.Attendees are responsible for all their travel and lodging expenses.</li>
<li>2017 4D Nucleome Annual Meeting information will be posted to the <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/meetings-and-committees/2017-4d-nucleome-annual-meeting” style=“color:rgb(17,85,204);font-family:Calibri,sans-serif”>4DN WIKI</a></li></ul></ul>
<ul><li>An ”<a href=“http://www.4dnucleome.org/outreach.html”>Education and Outreach</a>“ page launched on the 4DN Portal. It includes information for 4DN related tutorials and meetings. Thanks to 4DN consortium members, a total of 4 workshops and conference tutorials were given in 2016. In addition to 4DN annual meeting, 4DN consortium members will organize two conferences and one tutorial in 2017. </li></ul>
</h4>
<h4>
<ul><li>Members from three groups in 4DN (Leonid Mirny, Nils Gehlenborg, and Jian Ma) will jointly offer a data analysis tutorial during ISMB 2017 conference: <a href=“https://www.iscb.org/ismbeccb2017-program/tutorials#a3”>https://www.iscb.org/ismbeccb2017-program/tutorials#a3</a></li></ul>
<ul><li>4DN consortium's twitter account is 4DNucleome; please feel free to use @4DNucleome to emphasize that this tweet is related to 4DN. </li></ul>
<ul><li>4DN web portal featured new software tools, including HiGlass and 3D Genome Browser, as well as the previously featured WashU Genome Browser. See more at: http://www.4dnucleome.org/software.html</li></ul>
<ul><li>

Ordering information for HAP1 cells have been updated to the Cell Repository wiki page, thanks to Bas van Steensel. To date (April 17, 2017), a total of 13 4DN cell lines have become available.   

</li></ul>
</h4>
<h4>
<ul><li>A new working group “Joint 4D Nucleome Analysis” is formed. Job Dekker and Feng Yue will serve as co-chairs of this working group. Read about the <a href=“https://docs.google.com/document/d/1n4QPYp47CDINj2Rci2vl6xaxf-ihDxEoQMvyhwq_buA/edit”>objective, experimental design, and timeline</a> of this working group. Find more information on the wiki <a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/working-groups-list/joint-4dn-analysis”>Joint 4DN Analysis</a> page.</li></ul>
</h4>
<h4>
<ul><li>

Scientific Webinar Series this Month: 

</li>

<ul>

April 28, 2017

Presenter:Yongdae Shin (Princeton University) - Optical control of intracellular phase transitions

Presenter:Yodai Takei (Caltech) - Multiplexed dynamic imaging of genomic loci by combined CRISPR imaging and DNA sequential FISH

</ul>

</ul>
</h4>
<h4>
<ul style=“font-size:13.3333px”></ul>
</h4>

March 2017

<h4>
<ul><li>4DN membership and contact information.</li>
<ul><li>The latest <a href=“https://docs.google.com/spreadsheets/d/13gFjHcYEwYL2Xpr9-IHtJNYYnYlAQVdyXvCUeSzla6w/edit?usp=sharing”>4DN network contact list</a> is now updated in March 2017. NIH 4DN funded PIs are responsible for keeping the member information of their 4DN funded group current (PIs: please see 4DN wiki -> PIs and associates on how to update member information).</li>
<li>4DN wiki accounts and “4DN network contact list” have been synchronized. Ambiguous accounts that cannot be validated by the <a href=“https://docs.google.com/spreadsheets/d/13gFjHcYEwYL2Xpr9-IHtJNYYnYlAQVdyXvCUeSzla6w/edit?usp=sharing”>4DN network contact list</a> have been removed. </li></ul></ul>
<ul><li>Email groups for 4DN network and each Working Group have been organized to facilitate communication across subgroups of the consortium. Please check 4DN wiki (<a href=“https://sites.google.com/a/4dnucleome.org/4d-nucleome-wiki/listservs” style=“font-family:arial,sans-serif”>Email groups</a>) for detail.</li></ul>
</h4>
<h4>
<ul><li>The bioRxiv has created a channel for our preprints, which can be accessed here: <a href=“http://connect.biorxiv.org/relate/content/66” style=“color:rgb(17,85,204);font-family:arial,sans-serif”>http://connect.biorxiv.org/relate/content/66</a>. The content of the channel is manually curated. If you notice that one of your preprints is missing or incorrectly assigned to the list, please contact <a href=“mailto:nils@hms.harvard.edu” style=“color:rgb(17,85,204);background-color:transparent”>nils@hms.harvard.edu</a> or <a href=“mailto:leonid@mit.edu” style=“color:rgb(17,85,204);background-color:transparent”>leonid@mit.edu</a>. The fastest way to get your preprint included is to forward a link as soon as it has appeared on the bioRxiv. </li></ul>
</h4>
<h4>

<ul><li>Scientific Webinar Series this Month: </li></ul>

<ul>

March 24, 2017

Presenter: Naoki Kubo (UCSD) - Analysis of Chromatin Organization after Acute Loss of CTCF in Mouse Embryonic Stem Cells

Presenter: Anders Sejr Hansen (UC Berkeley) - CTCF and cohesin regulate chromatin loop stability with distinct dynamics

</ul>

</h4>

February 2017

<h4>
<ul><li>WiCell International Ordering Process (H1) is ready and available on 4DN Cell Repository. </li></ul>
<ul><li>The <a href=“http://www.4dnucleome.org/protocols.html” style=“background-color:transparent”>4DN Hi-C data generation protocol</a> has been approved.</li></ul>
<ul><li>Latest <a href=“http://www.4dnucleome.org/4dn-pre-prints.html” style=“background-color:transparent”>4DN Pre-prints</a> and news feed are now available on the 4DN Portal homepage.</li></ul>
<ul><li><a href=“https://doi.org/10.1101/103499”>The 4D Nucleome Project</a> perspective paper has been submitted.</li></ul>
</h4>
<ul><li>Scientific Webinar Series this Month:</li>

February 24, 2017

Presenter: Anastassia Vertii  (UMASS) -High-resolution mapping of nucleolar-associated chromatin in mouse cells
   Presenter: Sofia Quinodoz (CalTech) - Mapping RNA and DNA in higher-order nuclear structures

</ul>
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January 2017

<ul><li>The 4DN pre-prints are now accessible through the 4DN Portal, under Publications -> 4DN pre-prints. Note that only the pre-prints that are released on a public repository are accessible through the 4DN Portal. </li></ul>
<ul><li>Scientific Webinar Series this Month:</li></ul>

January 27, 2017
        Presenter: Ewan Birney - ChromoTrace: Simulation and reconstruction of 3D chromosome configuration by super-resolution microscopy.
        Presenter: Nan Hua - 3D genome structure calculation by data integration.

Tier I cells are available to order, for more information on how to order, check the Cell Repository wiki page.

</li></ul>
<ul><li>

The 2017 4DN Annual Meeting will be in Bethesda, MD on September 17-20, 2017 at the North Bethesda Marriott Hotel and Conference Center. More information regarding the meeting will be available soon.

</li></ul>

December 2016

<ul><li>NEW OH contact email - <a href=“mailto:oh@4dnucleome.org”>oh@4dnucleome.org</a>. Emails sent to 4dnucleome@gmail.com will be forwarded to the new email. Announcements should be sent the new 4DN Network email <a href=“mailto:4dn-network@4dnucleome.org” style=“text-decoration:underline”>4dn-network@4dnucleome.org</a></li></ul>
<ul><li>The Organizational Hub has updated the 4DN contact members list, after receiving the input from almost all contact PIs. 4DN Members updated Contact list is here <a href=“https://docs.google.com/spreadsheets/d/13gFjHcYEwYL2Xpr9-IHtJNYYnYlAQVdyXvCUeSzla6w/edit?usp=sharing” style=“text-decoration:underline”>4DN NETWORK LIST</a>. </li></ul>
<ul><li>The 4DN eGrant system for the Transformative Collaborative Project Award (TCPA) has been posted in the web portal - <a href=“http://www.4dnucleome.org/tcpa.html”>http://www.4dnucleome.org/tcpa.html</a>.</li></ul>
<ul><li>Don't forget to check the 4D Nucleome <a href=“https://twitter.com/4DNucleome”>Twitter</a>, <a href=“https://www.facebook.com/4DNucleome-1840252952876682/”>Facebook</a>, and <a href=“https://www.linkedin.com/in/4d-nucleome-857952126”>Linkedin</a> accounts.</li></ul>

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