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4DN Scientific Webinar Series
June 22, 2018
8:00-8:20 am Pacific Time, then 10 minutes Q&A
Nicola Neretti
PhD
Brown University
Title: Inference and Validation of Chromosomes' 3D Structure
Dr. Nicola Neretti is an Assistant Professor in the Department of Molecular Biology, Cell Biology, and Biochemistry, and in the Center for Computational Molecular Biology at Brown University. He received his PhD in Physics at Brown University, where he developed novel methods for wavelet design optimization. In his postdoctoral training, he developed signal processing techniques to study and model the auditory system. Dr. Neretti subsequently directed his research focus to computational biology and genomics thanks to an NIH Mentored Quantitative Research Development Award. His primary research interest is the study of genomic and epigenomic instability in aging and age-associated diseases. His research group has been among the first to characterize changes in chromosomes’ 3D structure and the activation of mobile genetic elements in cellular senescence and aging. Dr. Neretti’s laboratory current projects include: single cell transcriptomics in cellular senescence and aging; the study of transposable element activity; method development for chromosomes’ 3D structure inference combining genomics and microscopy data; and the use of cell-free DNA as a biomarker of aging and disease.
8:30-8:50 am Pacific Time, then 10 minutes Q&A
Andrew Field
PhD
Harvard Medical School
Title: Elucidating the role of nascent RNA at enhancers
Bio:
Andrew Field received his PhD in the lab of David Haussler at the University of California Santa Cruz and is currently a postdoctoral fellow under the direction of Karen Adelman at Harvard Medical School. Andrew is interested in transient cell states that underpin embryonic stem cell differentiation and development. In particular, he is investigating the role of enhancer commissioning and decommissioning in the transition from naive to primed stem cells. He is also probing the importance of specific enhancers and enhancer features at the cellular and mechanistic levels using a combination of bulk sequencing, single cell, and biochemical techniques.
HOW to Join the webinar:
Join by phone
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Click on the blue link - Join WebEx Meeting (above, not here) and you will be taken to a new window and asked to write your name and email - then click join. You might need to download the WebEx add on if you never used WebEx before. You will be taken to another window where you should choose call using computer (left circle) then you should be connected.
During Presentation:
ATTENDEES, PLEASE:
- MUTE YOUR COMPUTER MICROPHONE WHEN JOINING THE WEBINAR
- LET THE MODERATOR KNOW THAT YOU HAVE A QUESTION VIA CHAT
- QUESTIONS WILL BE ADDRESSED AT THE END OF EACH PRESENTATION, DURING THE DISCUSSION PERIODS.
In case we experience technical difficulties during the Webinars:
1. A new WebEx meeting invitation will be sent out immediately to the 4dn-network@4dnucleome.org email list.
2. If the problem with WebEx persists, OH will notify participants via 4dn-network@4dnucleome.org email to call 1.866.740.1260 and enter access code 8221626
3. Participants can find the Scientific Webinar slides presentations above under Scientific Webinar Series slides presentations.
Next Scientific Webinar Presentation
When: July 27, 2018
Moderated by: Andrew Belmont
Member from Tom Pastinen's group (Presenter and title will be determined by the group)
Member from Keji Zhao's group (Presenter and title will be determined by the group)