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===== Scientific Webinar Series slides presentations ===== | ===== Scientific Webinar Series slides presentations ===== | ||
- | **May 22, 2020** | + | **June 26, 2020** |
- | **Presenter: ****Minji Kim** (Jackson Laboratory) - "Chromatin folding dynamics in loop extrusion" ([[https://drive.google.com/open?id=1UjC3gXRCdKcMcbte88W0z4nKF0NZetk2|Link to presenter slides]]) | + | **Presenter: Karla Neugebauer ** (Yale University) - "A Structure-Function Analysis of Cajal Body Assembly" ([[https://drive.google.com/file/d/1zwihgzDU-XHJRoZz7rlxmuAyu4G1PUlr/view?usp=sharing|Link to presenter slides]]) |
- | **Presenter: Giancarlo Bonora ** (University of Washington) - "A time course multi-omics study of early mouse development at the single cell level" ([[https://drive.google.com/file/d/1HOMXlYBBnYPkqi_arEMxN9Lj2EpDXft7/view?usp=sharing|Link to presenter slides]]) | + | **Presenter: Charles Danko ** (Cornell University) - "Focal enhancer-promoter loops: Fact or Fiction" ([[https://drive.google.com/file/d/1ybYqo3Cuy6Mox_VhAVW6G43oZI-_GBK0/view?usp=sharing|Link to presenter slides]]) |
- | Previous Scientific Webinar presentations can be downloaded from the [[:4dn:scientific_webinar_series:scientific_webinar_presentation_archive|Scientific Webinar presentation archive page linked here]]. | + | Previous Scientific Webinar presentations can be downloaded from the [[:4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|Scientific Webinar presentation archive page linked here]]. |
===== 4DN Scientific Webinar Series ===== | ===== 4DN Scientific Webinar Series ===== | ||
- | ==== May 22, 2020 ==== | + | ==== June 26, 2020 ==== |
__**8:00-8:20 am Pacific Time**__ , 20 minutes talk, then 10 minutes Q&A | __**8:00-8:20 am Pacific Time**__ , 20 minutes talk, then 10 minutes Q&A | ||
- | {{:4dn:minji_kim_jax_photo_1.jpg?nolink&200x250|minji_kim_jax_photo_1.jpg}} | + | {{:4dn:phase1:neugebauerkarla.jpg?nolink&200x250|neugebauerkarla.jpg}} |
- | **Minji Kim** | + | **Karla Neugebauer** |
- | Postdoc | + | [[karla.neugebauer@yale.edu|]] |
- | [[Minji.Kim@jax.org|]] | + | Title: "A Structure-Function Analysis of Cajal Body Assembly " |
- | Title: "Chromatin folding dynamics in loop extrusion" | + | Karla Neugebauer holds a BS in Biology from Cornell University, a PhD in Neuroscience from UCSF. She switched gears to RNA biology as a postdoc with Mark Roth at Fred Hutchinson Cancer Research Center. There she participated in the initial description of the SR protein family of splicing regulators and was inspired to study RNA metabolism //in vivo// by combining imaging, genomics, and sequencing strategies. She studied splicing in relation to nuclear speckles and discovered that most introns are removed during the process, or co-transcriptionally. Her lab has shown that snRNP assembly occurs in membraneless organelles called Cajal bodies (CBs) and that depletion of the CB scaffolding protein coilin is lethal in zebrafish embryos, due to a deficit in splicing. She is currently Professor of Molecular Biophysics and Biochemistry and of Cell Biology at Yale University, where she is also Director of the Yale Center for RNA Science and Biomedicine. |
- | + | ||
- | Minji is a postdoc working with Drs. Yijun Ruan and Jeff Chuang at the Jackson Lab (JAX). She studies allele-specific chromatin interactions and chromatin dynamics, and develops computational tools along the way. Her BS, MS, and PhD degrees are from UC San Diego (UCSD) and University of Illinois at Urbana-Champaign (UIUC), all in electrical engineering. | + | |
__**8:30-8:50 am Pacific Time**__ , 20 minutes talk, then 10 minutes Q&A | __**8:30-8:50 am Pacific Time**__ , 20 minutes talk, then 10 minutes Q&A | ||
- | {{:4dn:gbonora_208250.jpg?nolink&200x250|gbonora_208250.jpg}} | + | {{:4dn:phase1:dankoheadshot2.jpg?nolink&200x250|dankoheadshot2.jpg}} |
- | **Giancarlo Bonora** | + | **Charles Danko** |
- | **Postdoc** | + | [[dankoc@gmail.com|]] |
- | [[gbonora@uw.edu|]] | + | Title: "Focal enhancer-promoter loops: Fact or Fiction" |
- | Title: "A time course multi-omics study of early mouse development at the single cell level" | + | Charles Danko is the Robert N. Noyce Assistant Professor at Cornell University. His primary research interest is to understand how DNA sequence encodes complex programs of gene expression. Danko played a vital role in developing assays that map the location of RNA polymerase (PRO-seq, ChRO-seq), and has led the development of computational tools which leverage this information to identify active functional elements (dREG). Danko has a long-standing interest in integrating maps of chromatin architecture and transcription to understand the dynamic interactions that encode the timing and levels of gene transcription. |
- | I am a postdoctoral fellow in the Noble lab in the Department of Genome Sciences at the University of Washington, Seattle. I apply computational approaches to the study of gene regulatory mechanisms, including the role of three-dimensional (3D) genome organization. For this project, in collaboration with the Disteche lab and other UW colleagues, I am investigating the cellular heterogeneity and dynamics of the structure of the mammalian genome and gene expression landscape during the process of random X-chromosome inactivation. | ||
===== HOW to Join the webinar: ===== | ===== HOW to Join the webinar: ===== | ||
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1. A new WebEx meeting invitation will be sent out immediately to the [[4dn-network@4dnucleome.org|]] email list. | 1. A new WebEx meeting invitation will be sent out immediately to the [[4dn-network@4dnucleome.org|]] email list. | ||
- | 2. If the problem with WebEx persists, OH will notify participants via [[4dn-network@4dnucleome.org|]] email to call [[:4dn:1.866.740.1260|]] and enter access code 8221626. | + | 2. If the problem with WebEx persists, OH will notify participants via [[4dn-network@4dnucleome.org|]] email to call [[:4dn:phase1:1.866.740.1260|]] and enter access code 8221626. |
3. Participants can find the Scientific Webinar slides presentations above under **Scientific Webinar Series slides presentations.** | 3. Participants can find the Scientific Webinar slides presentations above under **Scientific Webinar Series slides presentations.** | ||
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===== Next Scientific Webinar Presentation ===== | ===== Next Scientific Webinar Presentation ===== | ||
- | **When: June 26, 2020** | + | **When: ** |
- | + | ||
- | **Moderated by: Andrew Belmont** | + | |
- | Member from **Jan T. Liphardt**'**s group** (Presenter: TBD) | + | **Moderated by: TBD** |
- | Member from **John T. Lis (contact) Henning Lin, Warren R Zipfel's group** (Presenter: TBD) | + | Member from **Center**group** (Presenter: TBD) Member from **Center group** (Presenter: TBD) |
===== Calendar ===== | ===== Calendar ===== |