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--- 4dn:phase2:scientific_webinar [2025/07/18 08:05]
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+++ 4dn:phase2:scientific_webinar [2025/08/22 08:04] (current)
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@@ Line 25: / Line 25: @@
 ===== Scientific Webinar Series slides presentations =====
-**July 25, 2025**
+**August 22, 2025**
 **Zoom recording link**
-**Moderator: Sui Huang**
+**Moderator: Yuan Liu**
-**Presenter: Han Yang**// (University of California, San Francisco)//** - //“// ****//Functional Characterization of Schizophrenia Risk Variants Using PRIME Editing in Excitatory Neurons// ****//” //**  (Link to presenter slides)
+**Presenter: Jodi Lee **//(University of California, San Francisco) //**-** //**"Predictive modeling to assess the role of 3D genome folding in human congenital heart disease"**//  ([[https://drive.google.com/file/d/11mB2tB0l9egVjxAfJckfR3CKb3hy0qxe/view?usp=sharing|Link to presenter slides]])
-**Presenter: Nathan Zemke**// (////University of California San Diego)//** - //“// ****//Epigenetic and 3D genome reprogramming during the aging of human hippocampus// ****//”// ** (Link to presenter slides)
+**Presenter: Yanyu Zhu** //(Stanford University) //- **//“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”//**  ([[https://docs.google.com/presentation/d/1o9bXE1ZnWB0bxaXBYzDf1GE14dgzolUx/edit?usp=drive_link&ouid=105768913603538088409&rtpof=true&sd=true|Link to presenter slides]])
   * Scientific Webinar presentations (Phase 1) can be found [[https://wiki.4dnucleome.org/4dn:phase1:scientific_webinar_series:scientific_webinar_presentation_archive|here]].
@@ Line 40: / Line 40: @@
 ===== 4DN Scientific Webinar Series =====
-<font 16px/inherit;;inherit;;inherit>**July 25, 2025**</font>
+<font 16px/inherit;;inherit;;inherit>**August 22, 2025**</font>
 <font 14px/inherit;;inherit;;inherit>**8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)**</font>
-**Han Yang**
+**Jodi Lee**
-**Postdoctoral fellow**
+**Grad Student**
-[[Han.Yang@ucsf.edu|]]
+[[jodi.lee@gladstone.ucsf.edu|]]
-**Title: //“Functional Characterization of Schizophrenia Risk Variants Using PRIME Editing in Excitatory Neurons”// **
+**Title: //“Predictive modeling to assess the role of 3D genome folding in human congenital heart disease”// **
-Han Yang is a postdoctoral fellow in the Yin Shen Lab at the University of California, San Francisco. He earned his Ph.D. in Molecular Pathology from Peking University Health Science Center. Han's research focuses on developing and applying cutting-edge functional genomics tools to study the role of genetic variants in complex disease. Currently, he is leveraging the PRIME editing screens he co-developed to investigate how both common and rare schizophrenia risk variants affect excitatory neurons.
+Jodi is a 4th year graduate student studying genetics in Dr. Katherine Pollard’s Lab at the University of California, San Francisco. Jodi’s research focuses on creating and working with deep learning models to study the complex DNA sequence grammar regulating the genome. Currently, she is leveraging Cardiac-Akita, a DNA sequence to 3D genome folding deep learning model, to predict how genetic variants associated with congenital heart defects disrupt 3D genome contacts.
 <font 14px/inherit;;inherit;;inherit>**8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)**</font>
-**NathanZemke**
+**Yanyu Zhu**
-**Director of Single Cell Genomics at the Center for Epigenomic**
+**Postdoctoral Researcher**
-[[nzemke@health.ucsd.edu|]]
+[[yanyuzhu@stanford.edu|]]
-**Title: //“Epigenetic and 3D genome reprogramming during the aging of human hippocampus”// **
+**Title: //“High-resolution Dynamic Imaging of Chromatin DNA Communication using Oligo-LiveFISH”// **
-Nathan is Director of Single Cell Genomics at the Center for Epigenomics at UCSD. He explores principles of gene regulation in the context of chromatin organization from mammalian tissues. His work involves identifying functional cis-regulatory elements and mapping cell-type resolved chromatin architecture from complex mammalian tissue using multi-omic single-cell technologies.
+Yanyu Zhu is a postdoctoral researcher in Prof. Stanley Qi’s Lab in the Department of Bioengineering at Stanford University. He obtained his B.S. in Chemistry from Peking University and his Ph.D. in Chemistry from the University of Wisconsin–Madison. In collaboration with Prof. W. E. Moerner’s lab, he developed and applied a high-resolution, reagent-based DNA imaging platform, Oligo-LiveFISH, to investigate 3D chromatin dynamics in live cells. His current research focuses on applying Oligo-LiveFISH to study various biological questions such as the relationship between the 3D genome and gene regulation in real time, as well as investigating the dynamic process of DNA repair.
 The Webinar Series will be on the **4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.**
@@ Line 91: / Line 91: @@
 <font 16px/inherit;;inherit;;inherit>**Next Scientific Webinar Presentation**</font>
-**When: August 22, 2025**
-**Moderator: Taekjip Ha**
-  * **Presenter from Benoit Bruneau (contact), Katherine Pollard's team**
-  * **Presenter from Jennifer Phillips-Cremins (contact), Gerd Blobel, Lei Stanley Qi, Arjun Raj's team**

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