4DN Google Drive folder: https://drive.google.com/drive/folders/1Q1mzBETKDLLnMviloMVGCieBNNqKbP36?usp=sharing

Scientific Webinar Calendar: click here to add all the Scientific Webinar events to your personal calendar

Scientific Webinar Assignments (2021-2024): docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing

The 4DN Consortium Scientific Webinar Series is designed to promote sharing ideas and establishment of new collaborations among the consortium members. It features scientific presentations by 4DN member group. These presentations are focused on new discoveries, and new approaches and are not meant to be high-level summaries of deliverables/objectives of each project as in annual consortium meetings. Each group is strongly encouraged to present unpublished research. The PI of each member group may designate either themselves or members of their group to give the presentation.

The format of this webinar series will consist of hour-long online video conferences. Each Webinar will feature two presentations, with each presentation allocated 20’ of talk time followed by 10’ of discussion. All member groups of 4DN consortium are expected to present once in this round, although some centers may present twice given the size of their grants.

The Webinar organization committee has discussed and come up with a schedule for presentations after February 2021. See the schedule here: Scientific Webinar Assignment 2021-2024.

The schedule is ranked by funded project and the corresponding PI's last name. While the corresponding PI is put in the presentation slot, it is up to the corresponding PI to decide who in their team is to give the talk. It is encouraged that trainees are given the chance to present. If the corresponding PI wants to switch with someone else on the list in a mutual agreement, then she/he has the responsibility to arrange it and let the Webinar organization committee know.

Scientific Webinar Committee: Ana Pombo, Golnaz Vahedi, Sheng Zhong, Ting Wang, Wenbo Li, Sui Huang, Yin Shen, Taekjip Ha

October 27, 2023

Moderator: Yin Shen

Presenter: Ariel Pourmorady (Columbia University) - “A symmetry breaking process proposes noncoding functions for olfactory receptor RNAs” (Link to presenter slides)

Presenter: Bence Daniel (Stanford University) - “Macrophage plasticity in the 3-dimensional genome” (Link to presenter slides)

• Scientific Webinar presentations (Phase 1) can be found here.

• Scientific Webinar presentations (Phase 2) can be found here.

October 27, 2023

8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)

Ariel Pourmorady

MD-PhD Student

adp2164@cumc.columbia.edu

Title: “A symmetry breaking process proposes noncoding functions for olfactory receptor RNAs”

I am currently a 6th year MD-PhD student at Columbia University in the lab of Dr. Stavros Lomvardas. As a graduate student my research has been primarily focused on clarifying the genomic transformations that take place to facilitate olfactory receptor choice in the mouse main olfactory epithelium. I have used a variety of single-cell genomics technologies as well as mouse genetics to uncover a differentiation-dependent process whereby olfactory receptor genes compete for transcriptional selection. Broadly, I am interested in understanding how neurons employ gene regulatory programs—modifying chromatin state, nuclear architecture, and more—to support normal cell development and function.

8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)

Bence Daniel

Principal Scientist

bdaniel8@stanford.edu

Title: “ Macrophage plasticity in the 3-dimensional genome ” Bence Daniel is a Principal Scientist at Genentech where he is leading the Epigenetics and Chromatin Biology Research Program in the MPL-NGS Department. Bence was a postdoctoral fellow in the Satpathy lab at Stanford University where he studied the epigenetic regulation of T cell exhaustion in viral infection and cancer, and macrophage responses to inflammatory signals as part of the 4D Nucleome program. More specifically, he investigated how epigenetic programs and genome conformation affect macrophage plasticity, memory formation, and inflammatory signal integration.

The Webinar Series will be on the 4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.

4DN OH is inviting you to a scheduled Zoom meeting.

Topic: 4DN Scientific Webinar
Please download and import the following iCalendar (.ics) files to your calendar system.
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During Presentation:

ATTENDEES, PLEASE:

• MUTE YOUR COMPUTER MICROPHONE WHEN JOINING THE WEBINAR

• LET THE MODERATOR KNOW THAT YOU HAVE A QUESTION VIA CHAT

• QUESTIONS WILL BE ADDRESSED AT THE END OF EACH PRESENTATION, DURING THE DISCUSSION PERIODS

Next Scientific Webinar Presentation

When: January 26, 2024

Moderator: Sui Huang

• Presenter from Tomoko Yamada's team
• Presenter from Thomas Gregor (contact), Michael Levine, Jared Toettcher's team