4DN Google Drive folder: https://drive.google.com/drive/folders/1Q1mzBETKDLLnMviloMVGCieBNNqKbP36?usp=sharing

Scientific Webinar Calendar: click here to add all the Scientific Webinar events to your personal calendar

Scientific Webinar Assignments (2021-2024): docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing

The 4DN Consortium Scientific Webinar Series is designed to promote sharing ideas and establishment of new collaborations among the consortium members. It features scientific presentations by 4DN member group. These presentations are focused on new discoveries, and new approaches and are not meant to be high-level summaries of deliverables/objectives of each project as in annual consortium meetings. Each group is strongly encouraged to present unpublished research. The PI of each member group may designate either themselves or members of their group to give the presentation.

The format of this webinar series will consist of hour-long online video conferences. Each Webinar will feature two presentations, with each presentation allocated 20’ of talk time followed by 10’ of discussion. All member groups of 4DN consortium are expected to present once in this round, although some centers may present twice given the size of their grants.

The Webinar organization committee has discussed and come up with a schedule for presentations after February 2021. See the schedule here: Scientific Webinar Assignment 2021-2024.

The schedule is ranked by funded project and the corresponding PI's last name. While the corresponding PI is put in the presentation slot, it is up to the corresponding PI to decide who in their team is to give the talk. It is encouraged that trainees are given the chance to present. If the corresponding PI wants to switch with someone else on the list in a mutual agreement, then she/he has the responsibility to arrange it and let the Webinar organization committee know.

Scientific Webinar Committee: Ana Pombo, Golnaz Vahedi, Sheng Zhong, Ting Wang, Wenbo Li, Sui Huang, Yin Shen, Taekjip Ha

February 23, 2024

Moderator: Ting Wang

Presenter: Benxia Hu(University of Texas Health Science Center Houston) - “ m6A-MAPT-uaRNA regulates gene expression in Alzheimer’s disease“ (Link to presenter slides) Presenter: Alex Polyzos (Weill Cornell Medicine) - “ Mapping of 3D enhancer-promoter networks in early embryonic lineages and predictions of regulatory relationships” (Link to presenter slides)

• Scientific Webinar presentations (Phase 1) can be found here.

• Scientific Webinar presentations (Phase 2) can be found here.

February 23, 2024

8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)

Benxia Hu

Postdoc

Benxia.Hu@uth.tmc.edu

Title: “ m6A-MAPT-uaRNA regulates gene expression in Alzheimer’s disease“

Dr. Benxia Hu is a postdoctoral researcher in Dr. Wenbo Li’s lab at University of Texas Health Science Center Houston. He earned his Ph.D. from the Kunming Institute of Zoology, Chinese Academy of Sciences. Benxia's interest is on unraveling roles of 3D genome architectures in the human brains. Currently, his interest is to decipher the role of MAPT-uaRNA in the Alzheimer’s disease.

8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)TBD

Alex Polyzos

Assistant Professor

app2006@med.cornell.edu

Title: “ Mapping of 3D enhancer-promoter networks in early embryonic lineages and predictions of regulatory relationships ” Alex is an Assistant Professor of Molecular Biology, Research in Medicine in Weill Cornell Medicine. He joined Effie's Apostolou lab as a post-doc in 2017 and focused his research on investigating the organization of the 3D genome. His interest lies in characterizing the properties of 3D enhancer and promoter networks (referred to as HUB) and exploring how the rewiring of HUBs influences gene expression during somatic cell reprogramming, development and tumorigenesis.

The Webinar Series will be on the 4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.

4DN OH is inviting you to a scheduled Zoom meeting.

Topic: 4DN Scientific Webinar
Please download and import the following iCalendar (.ics) files to your calendar system.
Monthly: https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f

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During Presentation:

ATTENDEES, PLEASE:

• MUTE YOUR COMPUTER MICROPHONE WHEN JOINING THE WEBINAR

• LET THE MODERATOR KNOW THAT YOU HAVE A QUESTION VIA CHAT

• QUESTIONS WILL BE ADDRESSED AT THE END OF EACH PRESENTATION, DURING THE DISCUSSION PERIODS

Next Scientific Webinar Presentation

When: March 22, 2024

Moderator: Taekjip Ha

• Presenter from David Schatz (contact), Siyuan Wang's team
• Presenter from Yin Shen (contact), Arnold Kriegstein's team