4DN Google Drive folder: https://drive.google.com/drive/folders/1Q1mzBETKDLLnMviloMVGCieBNNqKbP36?usp=sharing

Scientific Webinar Calendar: click here to add all the Scientific Webinar events to your personal calendar

Scientific Webinar Assignments (2021-2024): docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing

The 4DN Consortium Scientific Webinar Series is designed to promote sharing ideas and establishment of new collaborations among the consortium members. It features scientific presentations by 4DN member group. These presentations are focused on new discoveries, and new approaches and are not meant to be high-level summaries of deliverables/objectives of each project as in annual consortium meetings. Each group is strongly encouraged to present unpublished research. The PI of each member group may designate either themselves or members of their group to give the presentation.

The format of this webinar series will consist of hour-long online video conferences. Each Webinar will feature two presentations, with each presentation allocated 20’ of talk time followed by 10’ of discussion. All member groups of 4DN consortium are expected to present once in this round, although some centers may present twice given the size of their grants.

The Webinar organization committee has discussed and come up with a schedule for presentations after February 2021. See the schedule here: Scientific Webinar Assignment 2021-2024.

The schedule is ranked by funded project and the corresponding PI's last name. While the corresponding PI is put in the presentation slot, it is up to the corresponding PI to decide who in their team is to give the talk. It is encouraged that trainees are given the chance to present. If the corresponding PI wants to switch with someone else on the list in a mutual agreement, then she/he has the responsibility to arrange it and let the Webinar organization committee know.

Scientific Webinar Committee: Ana Pombo, Golnaz Vahedi, Sheng Zhong, Ting Wang, Wenbo Li, Sui Huang, Yin Shen, Taekjip Ha

May 24, 2024

Moderator: Taekjip Ha

Presenter: Harshini Chandrashekar (University of Pennsylvania) - “Addressing the genome's structure-function relationship in Familial Alzheimer's Disease” (Link to presenter slides) Presenter: Johannes Stein (Harvard Medical School) - “Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level” (Link to presenter slides)

• Scientific Webinar presentations (Phase 1) can be found here.

• Scientific Webinar presentations (Phase 2) can be found here.

May 24, 2024

8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)

Harshini Chandrashekar

Graduate Student

hchand@seas.upenn.edu

Title: “Addressing the genome's structure-function relationship in Familial Alzheimer's Disease”

Harshini is a senior graduate student in Jennifer Cremins' lab at the University of Pennsylvania in the Department of Bioengineering. Prior to joining the Cremins Lab, she earned her Master's in Bioinformatics from Georgia Tech, Atlanta. Harshini's focus is on understanding how the 3D genome folding patterns, particularly chromatin loops, regulate gene expression in neurological disorders and neural activation model systems.

8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)

Johannes Stein

Postdoctoral fellow

Johannes.Stein@wyss.harvard.edu

Title: “Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level”

Johannes is a postdoctoral fellow in the labs of Ting Wu and George Church at the Wyss Institute and Harvard Medical School. With a background in physics, he ventured into biology during his PhD at the Max Planck Institute of Biochemistry in Germany, where he developed tools for quantitative super-resolution microscopy. His current research focus is enabling the visualization of nuclear organization at the single protein level.

The Webinar Series will be on the 4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.

4DN OH is inviting you to a scheduled Zoom meeting.

Topic: 4DN Scientific Webinar
Please download and import the following iCalendar (.ics) files to your calendar system.
Monthly: https://4dnucleome-org.zoom.us/meeting/tZ0ufu2trzMrG9SNYBoxiO0YxjK3-LEvoHWL/ics?icsToken=98tyKuGhrTIuH9WdsRiHRpx5A4r4LO_zmFxcjfpusibHDDhaTVPPLuhpYf9TNc7f

Join Zoom Meeting
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During Presentation:

ATTENDEES, PLEASE:

• MUTE YOUR COMPUTER MICROPHONE WHEN JOINING THE WEBINAR

• LET THE MODERATOR KNOW THAT YOU HAVE A QUESTION VIA CHAT

• QUESTIONS WILL BE ADDRESSED AT THE END OF EACH PRESENTATION, DURING THE DISCUSSION PERIODS

Next Scientific Webinar Presentation

When: June 28, 2024

Moderator: Wenbo Li

• Presenter from Bing Ren (contact), Catherine Dulac, Mario Nicodemi, Ana Pombo, Ting Wang, Xiaowei Zhuang's team
• Presenter from Yariu Diao's team