4DN Google Drive folder: https://drive.google.com/drive/folders/1Q1mzBETKDLLnMviloMVGCieBNNqKbP36?usp=sharing

Scientific Webinar Calendar: click here to add all the Scientific Webinar events to your personal calendar

Scientific Webinar Assignments (2021-2024): docs.google.com/spreadsheets/d/122eouLgJtMoCJNKmNhygufdU1qqEy-dDomxqqyQ1TxM/edit?usp=sharing

The 4DN Consortium Scientific Webinar Series is designed to promote sharing ideas and establishment of new collaborations among the consortium members. It features scientific presentations by 4DN member group. These presentations are focused on new discoveries, and new approaches and are not meant to be high-level summaries of deliverables/objectives of each project as in annual consortium meetings. Each group is strongly encouraged to present unpublished research. The PI of each member group may designate either themselves or members of their group to give the presentation.

The format of this webinar series will consist of hour-long online video conferences. Each Webinar will feature two presentations, with each presentation allocated 20’ of talk time followed by 10’ of discussion. All member groups of 4DN consortium are expected to present once in this round, although some centers may present twice given the size of their grants.

The Webinar organization committee has discussed and come up with a schedule for presentations after February 2021. See the schedule here: Scientific Webinar Assignment 2021-2024.

The schedule is ranked by funded project and the corresponding PI's last name. While the corresponding PI is put in the presentation slot, it is up to the corresponding PI to decide who in their team is to give the talk. It is encouraged that trainees are given the chance to present. If the corresponding PI wants to switch with someone else on the list in a mutual agreement, then she/he has the responsibility to arrange it and let the Webinar organization committee know.

Scientific Webinar Committee: Ana Pombo, Golnaz Vahedi, Sheng Zhong, Ting Wang, Wenbo Li, Sui Huang, Yin Shen, Taekjip Ha

June 28, 2024

Moderator: Wenbo Li

Presenter: Yang Xie (University of California San Diego) - “Droplet Hi-C for Fast and Scalable Profiling of Chromatin Architecture in Single Cells” (Link to presenter slides)

Presenter: Yarui Diao (Duke University) - “scHiCAR: a tri-modal single-cell technology for integrated transcriptome, epigenome, and 3D genome analysis in complex tissues” (Link to presenter slides)

• Scientific Webinar presentations (Phase 1) can be found here.

• Scientific Webinar presentations (Phase 2) can be found here.

June 28, 2024

8:00-8:30 am Pacific Time (20 minute presentation, 10 minute QA)

PHOTO

Yarui Diao

Assistant Professor

yarui.diao@duke.edu

Title: “scHiCAR: a tri-modal single-cell technology for integrated transcriptome, epigenome, and 3D genome analysis in complex tissues”

My research program, ‘Regeneration Genomics’, focuses on unraveling gene regulatory mechanisms driving cell fate changes during embryonic development and tissue regeneration, and understanding how these processes are disrupted in human diseases. In our quest to decode the fundamental mechanisms of gene regulation, we have also developed several cutting-edge genome profiling and engineering tools, including CREST-seq, HiCAR, CARGO-BioID, and scHiCAR, that benefit both our research and the broader scientific community. Prior to starting my own lab at Duke Cell Biology in 2018, I received my PhD from the Hong Kong University of Science and Technology, where I studied skeletal muscle differentiation and regeneration. I was also a Human Frontier Science Program (HFSP) Postdoctoral Fellow, trained with Dr. Bing Ren at UCSD.

8:30-9:00 am Pacific Time (20 minute presentation, 10 minute QA)

PHOTO

Yang Xie

Ph.D. Candidate

y2xie@health.ucsd.edu

Title: “Droplet Hi-C for Fast and Scalable Profiling of Chromatin Architecture in Single Cells” Yang Xie is currently a Ph.D. candidate in the Bing Ren lab at UC San Diego. His graduate research focuses on developing high-throughput single-cell sequencing techniques to explore the epigenomic diversity of mammalian brains. Utilizing these new methods, he aims to uncover how the epigenomic dysregulation contributes to neurodisorders and diseases.

The Webinar Series will be on the 4th Friday of each month from 8am-9am Pacific Time, 11am-12pm Eastern Time.

4DN OH is inviting you to a scheduled Zoom meeting.

Topic: 4DN Scientific Webinar
Please download and import the following iCalendar (.ics) files to your calendar system.
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Join Zoom Meeting
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During Presentation:

ATTENDEES, PLEASE:

• MUTE YOUR COMPUTER MICROPHONE WHEN JOINING THE WEBINAR

• LET THE MODERATOR KNOW THAT YOU HAVE A QUESTION VIA CHAT

• QUESTIONS WILL BE ADDRESSED AT THE END OF EACH PRESENTATION, DURING THE DISCUSSION PERIODS

Next Scientific Webinar Presentation

When: June 28, 2024

Moderator: Ting Wang

• Presenter from R. David Hawkins's team
• Presenter from Huaiying Zhang's team