Point people/organizers: Danwei Huangfu, Thomas Gregor, Yarui Diao, Bo Huang, Rene Maehr, Wenbo Li

4DN Google Drive folder: https://drive.google.com/drive/folders/1h1gU3Inwj837ZCJTyLAZ1ZUzjXOzpK9Z?usp=sharing

4DN Calendar: https://wiki.4dnucleome.org/4dn:calendar_4dn (click here to add this specific IG calendar to your personal calendar)

Agenda/Minutes: https://docs.google.com/document/d/1Pbx89KsVgrfJARryD47_zfE8RZNT58ptTlOnWzYtH5o/edit?usp=sharing

Meeting attendee spreadsheet: https://docs.google.com/spreadsheets/d/1P4-MTE0LDnD_J0VEZ3JtJioT5IMqELtDo23JO1XWtIw/edit?usp=sharing

Email list: perturbation-differentiation@4dnucleome.org

Slack channel: #ig-perturbation-differentiation

The goal of the Perturbation-Differentiation IG is to facilitate communication between various 4DN labs using differentiation systems to:

• Coordinate efforts
• Identify opportunities for collaboration
• Learn from each other’s experiences and the latest exciting findings
• Discover interesting chromatin biology during tissue differentiation and development

and facilitate discussions and foster collaborations focused on perturbation methods including the following topics:

• discussion of perturbation methods across an array of genomic and cellular contexts
• development of perturbative imaging approaches to dissect biological function
• approaches to scale up perturbation for functional screening
• functional screening readout with relevance to human health

***As of April 2023, IG meetings are cancelled until further interest.